ImmunoCult™ Mouse Treg Differentiation Supplement contains a combination of recombinant mouse and human cytokines and a small molecule optimized to promote the differentiation of mouse naïve CD4+ T cells into regulatory T cells (Tregs). This supplement is intended for use with RPMI 1640 Medium ...
产品名称: Mouse Treg Cell Differentiation Kit 货号: BR46108 规格: 24T 价格: 1200 品牌: BioRadars 说明书: 下载 产品简介: 首页|公司产品| 公司资讯|联系我们| 版权所有 2017-2020 北京佰瑞达生物科技有限公司 电话/传真:010-69360446 电子邮件:bioradars@yahoo.com 北京市丰台区方庄芳群园二区6号楼6...
Of all β2-integrins, T cells, including Treg, only express CD11a/CD18, termed lymphocyte function-associated antigen 1 (LFA-1), on their surface. In humans, loss-of-function mutations in the common subunit CD18 result in leukocyte adhesion deficiency type-1 (LAD-1). Cl...
The intricate balance of immune cells prevents the development of autoimmunity. T regulatory cells (Tregs) and Th17 cells derive from CD4+precursors in the presence of TGF-beta 1. The key cytokine that skews these cells toward the Th17 lineage is IL-6, while IL-2 promotes Treg di...
These cells are derived from Th2 cells reprogrammed by the presence of TGFβ, making IL-9 the probable mechanism by which TGFβ drives Th17 and Treg differentiation. Mouse and human IL-9 share 69% sequence homology at the nucleotide level and 57% at the protein level. Although mouse IL-9...
(CNS1), which is required for iTreg cell differentiation, do not develop fatal autoimmunity but present a pro-allergic phenotype[71]. The development of iTreg cells in the gut is shaped by the microbiota. Particularly relevant are the RORγt+iTreg cells which form the majority of iTreg ...
Objective To analyze the influence of mycophenolate mofetil on the differentiation and proliferation of CD4+CD25+Treg cells,and reveal its possible role in inducing immune tolerance.Methods Twenty-four 8-week-old SPF Balb/c mice were randomly divided into three groups,mycophenolate mofetil group(MMF)...
Treg/IL-17 Ratio and Treg Differentiation in Patients with COPD Chronic obstructive pulmonary disease (COPD) is characterized by chronic pulmonary and systematic inflammation. An abnormal adaptive immune response leads to an imbalance between pro- and anti-inflammatory processes. T-helper (Th), T-cyt...
IL-6, in combination with transforming growth factor (TGF)-β, is indispensable for Th17 differentiation from naïve CD4+ T cells, but that IL-6 also inhibits TGF-β-induced Treg differentiation[1]. 贮存 本网站销售的所有产品仅用于工业应用或者科学研究等非医疗目的,不可用于人类或动物的临床诊断...
Clearly, if PU.1 controls the differentiation of fetal phagocytes, it should be expressed before c-fms and other myeloid markers. Whole-mount in situ hybridization failed to detect any PU.1-positive cells at 9.5 dpc in the yolk sac or embryo (not shown) where c-fms is readily detected ...