Therefore, in this work, we build a knowledge-based database, named 'RegNetwork', of gene regulatory networks for human and mouse by collecting and integrating the documented regulatory interactions among transcription factors (TFs), microRNAs (miRNAs) and target genes from 25 selected databases. ...
Data availability All raw data and the Mascot output tables have been deposited to iProX and can be accessed with the accession IPX00081900. Additional information How to cite this article:Zhou, Q.et al. A mouse tissue transcription factor atlas.Nat. Commun.8,15089 doi: 10.1038/ncomms15089 ...
CXCR2,NCF4(neutrophil cytosolic factor 4), the transcription factorsMCL1,SPI1(encoding PU.1, an essential transcription factor for terminal granulopoiesis34,35) andJUNB, a transcription factor prominently expressed in late neutrotime which plays a vital role in...
For mouse mm10 genome assembly, use mm10.MA0139.1.RData (“AH104755”). For ENCODE SCREEN data, use hg38.SCREEN.GRCh38_CTCF.RData (“AH104730”) or mm10.SCREEN.mm10_CTCF.RData (“AH104756”) objects. The CTCF GRanges are named as <assembly>.<Database>. The FIMO-predicted data ...
Chromatin immunoprecipitation, DNase I hypersensitivity and transposase-accessibility assays combined with high-throughput sequencing enable the genome-wide study of chromatin dynamics, transcription factor binding and gene regulation. Although rapidly accumulating publicly available ChIP-seq, DNase-seq and ATAC...
Data were presented as mean ± SEM Full size image To explore how STAT3 promotes the expression of NMDARs, we screened potential binding sites of STAT3 in the promoter regions of GluN1, GluN2A, and GluN2B in a transcription factor database. We found one conserved GAS promoter element ...
et al. JASPAR, the open access database of transcription factor-binding profiles: new content and tools in the 2008 update. Nucleic Acids Res. 36, D102–D106 (2008) Article CAS Google Scholar Illingworth, R. S. & Bird, A. P. CpG islands –‘a rough guide’. FEBS Lett. 583, ...
A survey against the draft genome sequence and the cDNA/EST database of Ciona intestinalis identified a number of genes encoding transcription factors regulating a variety of processes including development. In the present study, we de... L Yamada,K Kobayashi,B Degnan,... 被引量: 727发表: 20...
Furthermore, Sp7 was shown as the key transcription factor that drives the self-regeneration of MDPSCs in vitro. However, whether CD24 positive cells are present in the developing tooth germs before birth was not documented. In this study, we investigated the native expressional dynamics of ...
Chromatin immunoprecipitation, DNase I hypersensitivity and transposase-accessibility assays combined with high-throughput sequencing enable the genome-wide study of chromatin dynamics, transcription factor binding and gene regulation. Although rapidly accumulating publicly available ChIP-seq, DNase-seq and ATAC...