The mouse mammary tumor virus (MMTV) promoter, that responds to glucocorticoids and progestins, contains a complex hormone response element (HRE) in the long terminal repeat (LTR) region covered by a phased nucleosome. Hormone treatment leads to alterations in chromatin structure that make the HRE...
Mouse transcription factors with canonical ChIP-seq peaks (displaying the typical strand asymmetry in read distribution around the putative binding site) outside of the D-loop.Georgi K. MarinovYun E. WangDavid ChanBarbar...
Bartel FO, Higuchi T and Spyropoulos DD (2000) Mouse models in the study of the Ets family of transcription factors. Oncogene 19,6443-6454.Bartel FO, Higuchi T, Spyropoulos DD. 2000. Mouse models in the study of the Ets family of transcription factors. Oncogene 19:6443-6454. doi: ...
The transcription factors SRY and SOX9 and RSPO1/WNT4/β-Catenin signaling act as antagonistic pathways to drive testis and ovary development respectively, from a common gonadal primordium in mouse embryos. In this work, we took advantage of a double knockout mouse model to study gonadal developme...
Elodie Portales-Casamar1, Frances M Sladek8, Philip H Bradley4 and Wyeth W Wasserman1* Abstract Here we present the Transcription Factor Encyclopedia (TFe), a new web-based compendium of mini review articles on transcription factors (TFs) that is founded on the principles of open access and ...
The transcription factors (ONECUT1, ONECUT2, and LHX1) allowed identification of horizontal cells. The cell group corresponding to Müller glia and astrocytes was identified based on expression of glutamine synthetase (GLUL), clusterin (CLU), and apolipoprotein E (APOE). The group of cells ...
22. Phosphorylation of eIF2α in response to intracellular stress induces the gene expression of transcription factors such as C/EBP homologous protein (CHOP) and activating transcription factor 3 (ATF3), leading to a stress response23. In the present study, we investigated the mode of ...
MRF4 (herculin/Myf-6) is one of the four member MyoD family of transcription factors identified by their ability to enforce skeletal muscle differentiation upon a wide variety of nonmuscle cell types. In this study the mouse germline MRF4 gene was disrupted by targeted recombination. Animals ho...
利用大肠杆菌谱系探索通过长期细菌进化改变突变的适应度效应 DOI: 10.1126/science.add1417 ④Science Advances:TrkB receptor interacts with mGlu2 receptor and mediates antipsychotic-like effects of mGlu2 receptor activation in the mouse TrkB受体与mGlu2受体相互作用并介导小鼠mGlu2受体激活的抗精神病药物的行为反...
13c), either because relevant transcription factors are absent or because other mechanisms of transposon silencing are effective. Importantly, at E16.5, where we observe expression from DMR regions in both Morc1tg/+ and Morc1tg/tg cells, we also observed a high ATAC-seq signal in both Morc1tg...