Mouse Prostate Cancer Cell Lines EstablishedMeanratiotoββ-actin(x103Meanratiotoββactin(x)
We assess the ability of adenovirus mediated expression of the Escherichia coli cytosine deaminase gene in conjunction with the prodrug 5-fluorocytosine to result in radiation sensitization in the mouse prostate cancer cell line RM-1 in vitro. To document cytotoxicity of gene therapy, RM-1 cells ...
Here, we converted mouse induced pluripotent stem cells (miPSCs) into prostate cancer stem-like cells with carcinoma microenvironment following exposure to conditioned medium (CM) derived from RM9, a mouse prostate cancer cell line. These transformed cells, termed as miPS-RM9CM, displayed CSCs ...
Effects of Docetaxel on two-dimensional and three-dimensional cell models. (a,b) Proliferation assays for a two-dimensional monolayer and a three-dimensional spheroid, for the prostate cancer cell line PC-3, treated with docetaxel. (c,d) Cell cycle analysis of a (c) monolayer and (d) sphe...
We have previously reported the development of a transgenic mouse model for prostate cancer derived from PB-Tag transgenic line 8247, henceforth designated the TRAMP (transgenic adenocarcinoma mouse prostate) model. We now describe the temporal and spatial consequences of transgene expression and report ...
The establishment, characterization, and tumorigenicity of a new epithelial cell line (PC-3) from a human prostatic adenocarcinoma metastatic to bone is re... M Kaighn - 《Invest Urol》 被引量: 3426发表: 1979年 Establishment of two human prostate cancer cell lines derived from a single bone ...
However AMD3100 also mobilized tumor cells at days 14 and 21 (P<0.0001), as shown by bioluminescent imaging. In conclusion, AMD3100 transiently enhances prostate cancer radiosensitivity, but induces cancer cell mobilization. 展开 关键词:CXCR4 AMD3100 Tumor cell mobilization Radiosensitivity ...
miR-100 represents TAMs-high expression in mouse breast cancer model and human breast cancer patients A syngeneic mouse breast cancer model was established with 4T1 mouse breast cancer cell line following the procedure in FigS. 1A. Mice were sacrificed when tumors grew up to 1000 mm3 and tumo...
In pathological conditions, pY216-GSK3β has been found in prostate cancer, and Src was found to promote this phosphorylation, and with it, cancer progression and invasion65. These other kinases are worth considering in the future and may be necessary to regulate sub-populations of GSK3. ...
et al. Androgen-regulated microRNA-135a decreases prostate cancer cell migration and invasion through downregulating ROCK1 and ROCK2. Oncogene 34, 2846–2855 (2015). Article CAS PubMed Google Scholar Wishart, T. M. et al. Combining comparative proteomics and molecular genetics uncovers regulators...