电话:400-800-2947 工作QQ:1843439339 (微信同号) 邮件:Biovector@163.com 手机:18901268599 地址:北京 已注册 详细信息 咨询记录(共0条) Human Prostate Cancer Cell Line (CWR-R1) Description: CWR-R1 is a cell line derived from the castration-recurrent human prostate cancer CWR22 xenograft. Highlights...
A well-characterized human cancer cell line derived from primary tumor of prostate cancer patients is described. Methods for screening compounds for the ability to affect a human tumor cell derived from human prostate cancer tissue cells, and method of screening for genes indicative or predictive of...
The phenotypic and functional differences between cells that initiate human breast tumors (cancer stem cells) and those that comprise the tumor bulk are difficult to study using only primary tumor tissue. We embarked on this study hypothesizing that breast cancer cell lines would contain analogous ...
We tested differential sensitivity to PT-112 in vitro across a panel of human prostate cancer cell lines (LNCap, LNCap-C4, LNCap-C4-2, DU-145, 22Rv1, VCap, PC-3) and the non-tumorigenic prostate cell line (RWPE-1). First, we evaluated the ability of PT-112 to inhibit cell growth ...
24. A method of prophylaxis or treatment of prostate cancer, comprising administering to a patient one or more doses of an immunogenic agent comprising three different allogeneic human prostate cell lines, wherein the cell lines are derived from tissues selected from the group consisting of: (a)...
Cytogenetic studies of a SV40T antigen immortalized human prostate epithelial cell line (P69SV40T) and its increasingly tumorigenic tumor sublines, designated M2182 and M15, were done with GTG-banding and multicolor fluorescence in situ hybridization (FISH). The parental line and each of the two...
In this study, we investigated the synergistic mechanism of anti-androgen and 5-fluorouracil (5-FU) combination therapy against castration-resistant prostate cancer (CRPC). Four prostate cancer cell lines, LNCaP, 22Rv1, DU145 and PC3, were examined for their growth dependency on androgens and ...
The main objective of this study is to perform the volatile profiling of four different PCa cell lines (22RV1, PC3; DU145; LNCaP) and one normal prostate epithelial cell line (PNT2) to prove the concept that VOCs emanated into the extracellular medium may discriminate PCa cells from normal...
However, the role of cyclin D1 in prostate cancer has not been previously studied in detail.METHODSSix human prostate cancer cell lines and cultures of normal human prostate cells were examined by Western and Northern blot analyses for levels of expression of the cyclin D1 protein and mRNA, ...
a similar enrichment of PR-2832 rearrangements and depletion of fusion-negative rearrangements near marks of active transcription profiled in several additional cell lines, including fusion-negative prostate cancer cell lines LNCaP and PC-3 as well as three cell lines derived from non-prostate lineages...