48 female KM mice were divided into four groups: control, oral, intraperitoneal injection and subcutaneous injection group. The mice in last three groups were treated with TG (50 mgkg(-1)) daily for 35 days, while the mice in control group were treated with parallel volume of sterile water...
Each mouse additionally received MPS in divided oral doses of 13 mg/kg for 10 consecutive days. Group B (the control group) received normal saline at the same location and same volume as those in Group A. Histological changes of the femoral heads were observed by electron microscopy at 3,...
When the volume of primary tumor reached around 500 mm3, surgical dissection was conducted under inhaled sevoflurane or intraperitoneal (i.p.) injection of propofol and anesthesia were maintained for three hours. Two weeks after surgical removal of primary tumor, the mice received sevoflurane ...
CD1 mice were treated with 10 mg/kg ASO-FII or ASO-CON by subcutaneous injection twice weekly for four consecutive weeks. Anesthetized mice were then sacrificed by cardiac puncture, with blood drawn into 1/9 volume of 3.8% sodium citrate and microcentrifuged (14,000 × g for ten ...
Oral administered particulate yeastderived glucan promotes hepatitis B virus clearance in a hydrodynamic injection mouse model. Yu X,Zhang D,Shi B,et al. PLo S One . 2015Yu X, Zhang D, Shi B, et al. Oral administered particulate yeast- derived glucan promotes hepatitis B virus clearance in...
We also compared the tumor growth of MDAs-ST with MDAs-OT weekly and concluded that tumors of MDAs-OT grew faster than MDAs-ST did at every time point, which was verified by the tumor volume and number of Ki67 positive cells (Fig. 1C,D). In conclusion, we successfully established MDAs...
After that, many researchers used BALB/c mice in a model where the production of specific IgE was studied after intraperitoneal injection with allergens such as rice protein, milk whey protein and tree nut (Birmingham et al., 2007, Chen et al., 2011, Gonipeta et al., 2009, Parvataneni ...
her group has achieved potent long-term silencing of polyQ transgenes. Injection of viral particles directly into the cerebellum and striatum of B05 and N171-82Q animals, respectively, results in a significant improvement in the disease phenotype in terms of both motor and neurological impairment ...
Female BALB/c mice (Charles River Labs, Germany) were primed with an intraperitoneal injection of thioglycollate broth, followed by an intraperitoneal challenge with zymosan (Sigma-Aldrich, USA) 24 hours later. After an additional 2 hours, the mice were perorally gavaged with a single dose...
Pharmacokinetic and tissue distribution profile of curculigoside after oral and intravenously injection administration in rats by liquid chromatography-mass spectrometry. Fitoterapia. 2015;101:64–72. Article CAS Google Scholar Tundis R, Loizzo MR, Bonesi M, Menichini F. Potential role of natural ...