Mouse IV Injection Procedure
Ortholog one2one βV-Spectrin σ 1 Spectrin β chain, brain (βIV spectrin) Ortholog one2one Spectrin α chain, RBC Spectrin α chain, RBC Ortholog one2one Spectrin β chain, RBC Spectrin β chain, RBC Ortholog one2one Spectrin brain 1 Spectrin β chain, brain 1 Ankyrins Apparent ortho...
Spatially charting molecular cell types at single-cell resolution across the 3D volume is critical for illustrating the molecular basis of brain anatomy and functions. Single-cell RNA sequencing has profiled molecular cell types in the mouse brain1,2, but cannot capture their spatial organization. H...
When the volume of primary tumor reached around 500 mm3, surgical dissection was conducted under inhaled sevoflurane or intraperitoneal (i.p.) injection of propofol and anesthesia were maintained for three hours. Two weeks after surgical removal of primary tumor, the mice received sevoflurane ...
(iv) the cortex (ctx), (v) the striatum (St), and (vi) the corpus callosum (cc, arrow) and cortex (ctx, arrowhead) co-localized with the marker for MBP (green). Scale bars = 50 µm. blue = Hoescht. (c) High magnification, confocal images of all lineages identified...
Injection sizes are held constant by using the same volume and concentration of dye, and checking each eye after each experiment to insure the dye injection is confined to the retina and does not invade the vitreous or lens. Samples from DiI injections that are not confined to the retina are...
Result demonstrates the curve of time-125I-NGF concentration in plasma after iv fit a two compartment open model. Distribution phase half life is 0.13 h, elimination phase half life is 3.68 h, mean plasma clearance is 0.125 L·h-1·kg-1, apparent volume of distribution is 0.697 L·kg-1...
her group has achieved potent long-term silencing of polyQ transgenes. Injection of viral particles directly into the cerebellum and striatum of B05 and N171-82Q animals, respectively, results in a significant improvement in the disease phenotype in terms of both motor and neurological impairment ...
Deep brain stimulation (DBS) relieves motor dysfunction in Parkinson’s disease, and other movement disorders. Here, we demonstrate the potential benefits of DBS in a model of ataxia by targeting the cerebellum, a major motor center in the brain. We use
This requires injection of the exact same amount of tracer in each animal which is generally assumed to be the case, but is rarely verified. Despite diligent attempts to inject the same amount of [3H]mannitol in different mice, systemic levels of [3H]mannitol varied, and it was necessary ...