02Single-cell transcriptome profling reveais neutrophil heterogeneity in homeostasis and infection ( Nature immunalogy,IF: 20.48 ) 样本:人外周血 03A cellular census of human peripheral immune cells identifes novel cell states in lung diseases (Clinical and Translational Medicine,IF:11.5) 样本:人外周...
While the neutrotime signature can be detected in both species and this overarching principle of neutrophil ontogeny is likely conserved across humans and mice, it is poorly understood which features of the neutrophil inflammatory response are shared across species. Furthermore, it is unclear which as...
Macrophage and neutrophil heterogeneity at single-cell spatial resolution in human inflammatory bowel disease. Nat Commun. 2023;14:4506. Article PubMed PubMed Central CAS Google Scholar Zhang Q, Jiang S, Schroeder A, Hu J, Li K, Zhang B, et al. Leveraging spatial transcriptomics data to ...
This novel technological advance offers for the first time the possibility of applying higher-throughput genetic modification and in vivo functional analysis to the neutrophil-lineage.doi:10.1096/fj.10-178517McDonald, J. U.Cortini, A.Rosas, M....
Cre recombinase and tdTomato expressed from a neutrophil-specific promoter allow highly specific genetic manipulation and labeling of neutrophils. Neutrophil granulocyte biology is a central issue of immunological research, but the lack of animal models
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Assessing the role of neutrophil apoptosis in the resolution of particle-induced pulmonary inflammation. Inhal Toxicol. 2003;15:1231–46. Article CAS PubMed Google Scholar Xiaojun W, Yan L, Hong X, Xianghong Z, Shifeng L, Dingjie X, et al. Acetylated α-Tubulin Regulated by N-Acetyl-...
Here, we have used single-cell RNA sequencing to profile more than 1600 single HSPCs, and deep sequencing has enabled detection of an average of 6558 protein-coding genes per cell. Index sorting, in combination with broad sorting gates, allowed us to retrospectively assign cells to 12 commonly...
Tani M, Fuentes ME, Peterson JW, et al. Neutrophil infiltration, glial reaction, and neurological disease in transgenic mice expressing the chemokine N51/KC in oligodendrocytes. J Clin Invest. Godiska R, Chantry D, Dietsch GN, et al. Chemokine expression in murine experimental allergic encephalo...
4-week and 8-week unique proteins in the skin and 8-week unique proteins in the intestine were shown in the immune process including defense response to Gram-positive bacterium, neutrophil degranulation, NF-kappa B signaling and IL-2 signaling pathway. The specific expression of immunomodulatory ...