Western blotting analysis of autophagy biomarkers, including the accumu- lation of LC3-II, the conversion of LC3-I to LC3-II, p62 degradation, and mTOR dephosphorylation (Fig. 1E–I), further confirm the inhibitory effects of FSH on oxidative stress-induced autophagy. The inhibition of ...
Western blotting analysis of autophagy biomarkers, including the accumu- lation of LC3-II, the conversion of LC3-I to LC3-II, p62 degradation, and mTOR dephosphorylation (Fig. 1E–I), further confirm the inhibitory effects of FSH on oxidative stress-induced autophagy. The inhibition of ...
Consequently, we have analyzed the effect of Gal3 in the LPS- induced model of endotoxemia (5 mg/kg) including (i) mortality rate, (ii) acute effect of LPS challenge (1 h) on membrane-bound Gal3 on circulating immune cells, (iii) delayed effect of LPS challenge (36 h) on Gal3 ...
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International Journal of Molecular Sciences Article Investigating Immune Responses to the scAAV9-HEXM Gene Therapy Treatment in Tay–Sachs Disease and Sandhoff Disease Mouse Models Shalini Kot 1,† , Subha Karumuthil-Melethil 2,†, Evan Woodley 1, Violeta Zaric 2,3, Patrick Thompson 4, ...