Western blotting analysis of autophagy biomarkers, including the accumu- lation of LC3-II, the conversion of LC3-I to LC3-II, p62 degradation, and mTOR dephosphorylation (Fig. 1E–I), further confirm the inhibitory effects of FSH on oxidative stress-induced autophagy. The inhibition of ...
Western blotting analysis of autophagy biomarkers, including the accumu- lation of LC3-II, the conversion of LC3-I to LC3-II, p62 degradation, and mTOR dephosphorylation (Fig. 1E–I), further confirm the inhibitory effects of FSH on oxidative stress-induced autophagy. The inhibition of ...
(B,D,F), ultrastructural observations. Scale bars: (B,F), 5 µm; (D), 2 µm. (H) Immunofluorescence of Iba1 showing a normal patter in microglial cells staining. (I) When animals were treated with LPS microglial cells activate and proliferate. Scale bars (H,I): 100 µm. 3...
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It was found that the scAAV9-HEXM treatment induced a T and B cell immune response to the viral capsid and the expressed human protein in TSD and SD mice. 2. Results To evaluate the immunocompetency of SD and TSD mouse models, and the im- mune response to gene therapy treatment, adult...