In C. elegans, it was shown that 18% of the 352 verified alternative exons showed a larger than fourfold change in alternative splic- ing during its development from embryo to adult, includ- ing larval stages [9]. In humans, mice, chickens and Xenopus, a well-known example is provided ...
No sperm or eggs were used in the development of the embryo model. Instead, by guiding the three different kinds of stem cells that are present in early mammalian development to the stage where they begin interacting, the researchers were able to mimic natural processes in the laboratory....
(PFA) in 0.05 M PBS solution for two days at 4 °C before storing in 0.05 M PBS at 4 °C until use. All embryos were characterized according to the Theiler Staging (TS) Criteria for Mouse Embryo Development86. We used E11.5 for TS19, E13.5 for TS21, E15.5 for TS24...
Kosugi, I, Shinmura, Y, Kawasaki, H, Arai, Y, Li, RY, Baba, S (2000) Cytomegalovirus infection of the central nervous system stem cells from mouse embryo: a model for developmental brain disorders induced by cytomegalovirus. Lab Invest 80: pp. 1373-1383...
Mouse Early Embryo Development Embryonic development is the generation of a multicellular organism from a single cell. During this process, tissues and organs are differentiated and positioned at different parts of the organism. In animals, Embryonic development consists of 4 stages: Cleavage, Patterning...
Expression of INK4 Inhibitors of Cyclin during Mouse Brain Development1 Kinases In situ hybridization of mouse embryo sections demonstrated expression of mRNAs encoding two polypeptide inhibitors (p18INK4c and p19INK4d) of cyclin D-dep... F Zindy,H Soares,J Morgan,... - 《Cell Growth Differ》...
Mammalian development is associated with considerable changes in global DNA methylation levels at times of genomic reprogramming. Normal DNA methylation is
m, In situ hybridization for Nhlh1 and Nhlh2 on sagittal sections of the E115 mouse embryo (Allen Brain Atlas). n, RNA in situ hybridization of mouse embryonic brain at the indicated time points, showing genes relevant to the cortical lineage (image credit: Allen Institute). Each subpanel...
Y.Cytomegalovirus infection of the central nervous systemstem cells from mouse embryo:a model for developmental braindisorders induced by cytomegalovirus... S Kosu - 《Laboratory Investigation》 被引量: 172发表: 2000年 Developmental disorders of the mouse brain induced by murine cytomegalovirus: Animal...
A mouse embryo (blastocyst) that has paused its development due to nutrient depletion. Credit: Jiajia Ye It's challenging to sustain a pregnancy when food is short, or conditions are otherwise tough. That's why many mammalian embryos can postpone their growth to get through periods of environme...