Nevertheless, both Zn2a and Zn2b were found to bind methyl viologen bis(hexafluorophosphate) (V12) with a similar strength as Zn1 (Fig. 4e)27. 1H NMR studies revealed that upon binding of the guest, both Zn2a and Zn2b underwent significant structural changes (Fig. 4a–d). The signals ...
Finally, this behavioral approach enabled us to quantify the relative strength of motor planning and sensory integration, by taking the normalized difference of the velocity modulation for negative and positive temporal lags. In line with previous lesion and inactivation approaches26,27,28,29, the rel...
Path analysis of strength, spasticity, gross motor function, and health-related quality of life in children with spastic cerebral palsy BACKGROUND: Measures of health-related quality of life may predict the future status of individuals with illnesses, and could therefore be a good indicator... Par...
Stroke scales usually convert motor status to a score along an ordinal scale and do not provide a permanent recording of motor performance. Computerized methods sensitive to small changes in neurological status may be of value for studying and measuring stroke recovery.We developed a computerized dyna...
Co-adaptation can combine the strengths of decoder and user adaptation by leveraging interplay between the two learners. For example, because users learn encoders that are influenced by the decoder, gradual changes to a decoder could progressively shape user learning. By encouraging users to form ...
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The subjective report was recorded on a 6 point scale ranging from 0 to 5. This score was first used to evaluate how participants’ awareness of a perceptual-motor conflict was modulated by the presence of an external perturbation (angular deviation) varying in strength. In addition, this data...
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Scale bar, 200 μm. n = 34 animals. c ChAT+ neuron number in the cPPN of runners and non-running controls that were injected with AAV-DIO- mRuby2 or AAV-DIO-ChAT. n = 5 animals per group. Nonparametric Kruskal–Wallis test followed by Dunn’s correction. d ChAT ...
A fundamental hallmark of motor actions is the flexibility of the timing, speed and strength that is central to rapid adaptation to the ever-changing world around us. This is particularly apparent during locomotion—a behavior that involves full-body coordination characterized by sudden changes in sp...