The term "motor neuron disease" refers to a variety of devastating neurological disorders characterized by a generalized degeneration of motoneurons. The common clinical manifestations of such disorders are progressive muscle weakness and often death by respiratory failure. Inherited and sporadic forms ...
Motor Neuron Disease: Pathophysiology, Diagnosis, and ManagementLaura A. Foster MD aMohammad Kian Salajegheh MD bThe American Journal of Medicine
changes in background activity ofalpha motor neuronsand interneurons have been implicated as important factors in the pathophysiology as well (Pearson & Gordon, 2000b). The spasticity produced byUMN lesionsis caused by lesions in descending tracts, such as the reticulospinal tract (Bucy, Keplinger,...
In this Review, we use a layer-specific and cell-specific approach to integrate physiological accounts of this motor cortex microcircuit with the pathophysiology of neurodegenerative diseases affecting motor functions. In doing so we can begin to link motor microcircuit pathology to specific disease ...
RegisterLog in Sign up with one click: Facebook Twitter Google Share on Facebook motor cell Medical [′mōd·ər ‚sel] (botany) bulliform cell (physiology) An efferent nerve cell in the anterior horn of the spinal cord. McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyr...
Clinical Neurophysiology of Motor Neuron Diseases豆瓣评分:0.0 简介:The volume summarizes the most recent knowledge in the field of motor system (upper and lower motor neuron) physiology and pathophysiology as related to diseases of this system. It cove
The spinal pathophysiology of spasticity — from a basic science point of view. Acta Physiol. (Oxf.) 189, 171–180 (2007). Article CAS Google Scholar Levin, M. F., Selles, R. W., Verheul, M. H. & Meijer, O. G. Deficits in the coordination of agonist and antagonist muscles in ...
motor neuron lesions is essential. Spasticity management is a major issue that requires attention due to the profound disability incurred by patients. It can lead to a restriction in the activity, pain, weakness, and contractures. Optimal management requires an understanding of the pathophysiology...
There are still considerable unknowns when it comes to the pathophysiology of the disease, diagnostic criteria and optimal treatment approach (Yeh et al., 2020). Multifocal motor neuropathy is not simply a demyelinating neuropathy. There are likely multiple events driven by antibody mediated damage ...
Although overactive gamma motor neurons may be involved in causing this phenomenon, changes in background activity of alpha motor neurons and interneurons have been implicated as important factors in the pathophysiology as well (Pearson & Gordon, 2000b). The spasticity produced by UMN lesions is ...