On the other hand, this structural key can be optimized for the compounds present in the database to be investigated. Hence, fingerprints were developed to overcome the shortcomings of structural keys. A fingerprint is a boolean array, but in contrast to a structural key the meaning of any ...
(Arslanet al., 2014; Nunezet al., 2015). Cas1/Cas2 cannot, however, insert unprocessed sequences; meaning additional factors are required in vivo. As described above, these include RecBCD in Gram-negative bacteria and AddAB in Gram-positives that trim the 5′-ends of the protospacer...
AS:Which of your songs has the most surprising meaning behind it? The Callouts: “Reverse Clooney” — the song is about the movieSpeedas a reverse Clooney is a Sandra Bullock. There’s a group sing along “your last day” and it’s about the woman in the movie who plays Helen...
When projected to this new reaction coordinate with the distance between two Arg arms, it is easy to see the bound basin displays a 0.5 nm larger separation in the two Arg arms than the non-bound basin, meaning in the unbound state the arginine arms are much closer to each other [...
The presence of the 8CM in a large family of proteins (around 500 sequences currently present in databases) having very different functions allows to propose that this is a motif that has essentially a structural and evolutionary meaning, but that does not bear in itself a functional role. The...