Mosaicism is the occurrence in an organism of two or more genetically distinct cell populations derived from the same individual. In human genetics, the consequences of aneuploidy or gene mutation can be less severe if the affected individual also contains some normal cells.Latest...
(Genetics) the occurrence of different types of cells side by side in the same organism Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014 ...
The case of a 5-month-old male infant with 18p- mosaic, who has intractable seizures and severe ophthalmological abnormalities in addition to many clinical manifestations usually described in the 18p- syndrome, is reported. The proportions of abnormal cells are 7–8% in blood and 55% in skin...
Mosaicism and clinical genetics. Am J Med Genet C Semin Med Genet. 2014;166C:397–405. Google Scholar Gajecka M. Unrevealed mosaicism in the next-generation sequencing era. Mol Genet Genomics. 2016;291:513–530. CAS Google Scholar Happle R. Gonosomal versus somatogonadal mosaicism: what ...
4.(Genetics)geneticsanother name forchimera4 5.(Surveying) an assembly of aerial photographs forming a composite picture of a large area on the ground 6.(Electrical Engineering) a light-sensitive surface on a television camera tube, consisting of a large number of granules of photoemissive materi...
Genetics HI is typically a sporadic condition and data are strongest for mosaicism as the genetic etiology. Mosaicism occurs when there are two different populations of cells during embryologic development, often due to mutation or chromosomal nondisjunction in one cell line. The whorled pattern of ...
关注 Natalia Krawczynska Gdańsk Medical University Genetics | Medicine 关注 Jolanta Wierzba Gdańsk Medical University Medicine | Biology 关注 Bartosz Wasag Gdańsk Medical University Biology | Cancer research 相关研究 High rate of mosaicism in individuals with Cornelia de Lange syndrome Sylvia A...
Human Genetics Aims and scope Submit manuscript Bogdan Kałuzewski, Danuta Podkul, Irena Zaborowska, Teresa Moruzgała & Lucjusz Jakubowski 1563 Accesses 1 Citation 1 Altmetric Explore all metrics Summary A 3-year-old boy from twin pregnancy with the features of marked dystrophia from ...
in each cell. Cells with 1q gain were observed on at least three slides per patient.d, Copy number profiling of single nuclei from patient 3 brain tissue confirming the presence of chr1q tetrasomy in approximately 30% of nuclei. Credit:Nature Genetics(2023). DOI: 10.1038/s41588-023-01547...
Medical geneticsNearly every mammalian cell division is accompanied by a mutational event that becomes fixed in a daughter cell. When carried forward to additional cell progeny, a clone of variant cells can emerge. As a result, mammals are complex mosaics of clones that are genetically distinct ...