Recent studies have shown that the expression of PD-L1 on other immune cells, such as tumor-infiltrating lymphocytes [59] and DCs [60], can also affect the efficacy of ICB therapy. Our study proposes that the expression of PD-L1 on monocytes plays a crucial role in the response process ...
For the PPMI cohort, blood samples were centrally collected and processed as reported by the study’s related documentation (www.ppmi-info.org) and as previously reported [45]. Cell type composition (percentage of neutrophils, lymphocytes, monocytes, basophils, eosinophils) was provided as well wit...
The discovery of integrins, a vastly important family of cell surface receptors that mediate adhesion, cell migration and signal transduction, resulted from studies aiming to identify the adhesion receptors on peripheral blood monocytes and lymphocytes, as well as their cognate ligands on activated ...