However, human sLAG3 has been suggested to act as a co-inhibitor of immune responses by impairing monocyte differentiation and antigen presenting capability preventing their induction of T cell proliferation [10, 11]. We hypothesize therefore that sLAG3 acts as a coinhibitory immune modulator ...
Abbreviations: OR—odds ratio; PD-L1—Programmed death-ligand 1; VISTA—V-domain immunoglobulin suppressor of T cell activation; L—low expression; H—high expression; LVI—lymphovascular invasion; NLR—neutrophil-to-lymphocyte ratio; PLR—platelet-to-lymphocyte ratio; LMR—lymphocyte-to-monocyte ...