20070036789 Neutralizable Epitope of HGF and Neutralizing Antibody Binding to the Same February, 2007 Chung 20070031416 Use of antibody February, 2007 Shoji et al. 7179892 Humanized antibodies that recognize beta amyloid peptide February, 2007 Basi et al. 7179606 IG heavy chain, IG kappa, IG lamb...
The present invention is directed toward a monoclonal antibody to fibroblast growth factor receptor 2, a pharmaceutical composition comprising same, and methods of treatment compris
The present invention is directed toward a neutralizing monoclonal antibody to basic fibroblast growth factor, a pharmaceutical composition comprising same, and methods of treatment
Ficlatuzumab (AV‐299; SCH 900105), a humanized IgG 1 κ HGF inhibitory monoclonal antibody, prevents HGF/c‐Met pathway ligand–mediated activation. This phase 1b study assessed the safety/tolerability, pharmacokinetics/pharmacodynamics, and antitumor activity of ficlatuzumab plus gefitinib in ...
Journal of Clinical Oncology↵ Mok T , Tan E , Park K , et al . Randomized phase II study of ficlatuzumab (formerly AV-299), an anti-hepatocyte growth factor (HGF) monoclonal antibody (MAb) in combination with gefitinib (G... H Bartelink,H Jones,N Antonini,... - 《Journal of ...