During the past several decades, monoclonals have found tremendous applications in diagnostics, therapeutics, and drug targeting. The diagnosis of any infectious disease often requires the demonstration of the pathogen or a specific antibody against the pathogen or its toxin. In some infectious diseases...
Onartuzumab, a monovalent monoclonal antibody against the c-Met receptor, has shown promising activity in preclinical models. Notably, a response was observed in Met-dependent models, such as those with paracrine or autocrine stimulation with the Met ligand, the hepatocyte growth factor (HGF) or ...
Mouse anti-cMet monoclonal antibody linked to gadolinium diethylenetriamine pentaacetic acid conjugated to biotinylated bovine serum albumin -- Molecular Imaging and Contrast Agent Database (MICAD)Excerpt The hepatocyte growth factor (HGF) is ... A Chopra - 《National Center for Biotechnology Information...
Isolated monoclonal antibodies which bind to human c-Met, the hepatocyte growth factor receptor, and related antibody-based compositions and molecules, are disclosed. Pharmaceutical compositions comprising the antibodies and therapeutic and diagnostic methods for using the antibodies are also disclosed.收藏...
A monovalent human monoclonal antibody or an antigen-binding fragment thereof(Fab) is provided to be able to induce the apoptosis of tumor cells in vitro without a cross-linker by being specifically bound to tumor necrosis factor(TNF)-related apoptosis-inducing ligand(TRAIL) death receptor5(DR5)...
Antibody 克隆号 5IL6 抗原 Recombinant human IL-6. 偶联物 Unconjugated 形式 Liquid 浓度 1.0 mg/mL 纯化类型 Protein A 保存液 PBS 内含物 no preservative 保存条件 -20°C 运输条件 Ambient (domestic); Wet ice (international) RRID AB_223576 ...
Antibody 克隆号 7IL6 抗原 Recombinant human IL-6. 偶联物 Biotin 形式 Liquid 浓度 0.5 mg/mL 纯化类型 Protein G 保存液 PBS with 4% BSA 内含物 proprietary Preservative 保存条件 -20°C 运输条件 Ambient (domestic); Wet ice (international) RRID AB_223577 产品详...
Antibody 克隆号 505E9A12A3 抗原 Purified recombinant human IL-6. 偶联物 Unconjugated 形式 Liquid 浓度 1 mg/mL 纯化类型 Protein A 保存液 PBS, pH 7.4 内含物 no preservative 保存条件 4° C 运输条件 Ambient (domestic); Wet ice (international) RRID AB_2536256 ...
26 The aim of this study was to determine the inhibitory role of SAIT301, a Met monoclonal antibody, in NPC cell lines for cancer therapy. The results of this study conclude that SAIT301 inhibited HGF-induced invasion and migration in both HONE1 and HNE1 cells (Figure 1). At this point...
Phase Ib study of ficlatuzumab (formerly AV-299), an anti-hepatocyte growth factor (HGF) monoclonal antibody (MAb) in combination with gefitinib (G) in Asi... Phase Ib study of ficlatuzumab (for-merly AV-299), an anti-hepatocyte growth factor (HGF) monoclonal antibody (MAb) in ...