PB2112 COEXISTENCE OF MONOCLONAL B- CELL POPULATION IN PATIENTS WITH NEWLY DIAGNOSED MULTIPLE MYELOMA; INCIDENCE, IMMUNOPHENOTYPING AND CLINICAL CHARACTERIZATIONdoi:10.1097/01.HS9.0000566932.71036.62Cohen, Y.Cohen, I.Perry, C.Avivi, I.Kay, S.
Many modern applications of antibodies in research, medicine, veterinary medicine, and other fields rely heavily, although not exclusively, on monoclonal antibodies. By definition, amonoclonal antibodypopulation is derived from a clonal population of B lineage cells. Therefore, all of the molecules expr...
( 1991 ) The leukemic B-cell population of patients with monoclonal lymphocytosis of undetermined significance (MLUS) are functionally distinct from the chronic lymphocytic leukemia (B-CLL) derived cell population . Leukemia Research , 15 , 715 – 719 ....
ASSOCIATION BETWEEN INFECTIOUS AGENTS AND MONOCLONAL B-CELL LYMPHOCYTOSIS (MBL) IN THE GENERAL POPULATION 来自 ResearchGate 喜欢 0 阅读量: 10 作者: J Almeida 摘要: It was recently proposed that in Jurkat cells, after inhibition of respiration by NO, glycolytically generated ATP plays a critical ...
The F4/80 antigen is expressed by a majority of mature macrophages and is one of the best markers for this population of cells. However, other cell types, such as peritoneal eosinophils, Langerhans cells, and some other dendritic cell subtypes, have been reported to express this antigen as ...
mRNA bindingprotein bindingmRNA (2'-O-methyladenosine-N6-)-methyltransferase activityS-adenosyl-L-methionine bindingRNA processing factor 参与通路 mRNA splicing, via spliceosomegene expressionstem cell population maintenancemRNA destabilizationmRNA methylation...
Monoclonal B cell lymphocytosis (MBL) is both a marker of immune senescence and a potential precursor of B cell malignancy. Most MBL populations have a chronic lymphocytic leukemia-like (CLL-like) immunophenotype, but those that are CD5-negative (non-CLL-like) are also recognized and may repre...
Box 1 Updated definition of MGRS The following consensus view of monoclonal gammopathy of renal significance (MGRS) has emerged. The term MGRS applies specifically to any B cell or plasma cell clonal lymphoproliferation with both of the following characteristics: One or more kidney lesions that are...
Maternal vaccine strategies to specifically target this breast milk B-cell population may be necessary to achieve safe breastfeeding for all HIV-1-exposed infants. INTRODUCTION Mother-to-child transmission accounts for B260,000 new HIV-1 infections annually,1 with a majority occurring in sub- ...
A monoclonal antibody (MAb) is an antibody of a single specificity produced by cells derived from a single B cell clone. In most cases, the MAb is derived from mice (and is xenogeneic) as illustrated in Figure 35-7. MAbs are increasingly being used diagnostically to assess immunocompetence...