Monoamine oxidase inhibitors have been synthesized with two important properties, reversibility and selectivity, to improve targeting of the central nervous system and to reduce their potentially dangerous drug-drug and drug-food interactions. Precisely because required dietary restrictions, avoidance of ...
The present invention provides a group of tobacco alkaloids, tobacco extract, Yerbamat茅 extract, and an extract of chewing gum and lozenges which are modulators of monoamine oxidase (MAO) activity (i.e., compounds and substances which inhibit MAO enzyme and prevent its biological activity). The...
Monoamine oxidase inhibitors: MAOIs are effective for some people with major depression who do not respond to other antidepressants. They are also effective for the treatment of panic disorder and bipolar depression. MAOIs approved for the treatment of depression are phenelzine (Nardil), ...
1. The principal routes of metabolism of the following monoamine oxidase inhibitors (MAOIs) are described: phenelzine, tranylcypromine, pargyline, deprenyl, moclobemide, and brofaromine. 2. Acetylation of phenelzine appears to be a minor metabolic pathway. Phenelzine is a substrate as well as an...
The animal pharmacology of the monoamine oxidase inhibitors (MAOIs*) has been reviewed previously by Zirkle and Kaiser (1964), Biel et al. (1964), Pscheidt (1964), Horita (1967), and Jacob and Simon (1968).
A series of substituted p-aminophenethylamines and some related compounds were examined with regards to the inhibition of monoamine oxidase (MAO) in vivo inside and outside 5-hydroxytryptaminergic neurones in the rat hypothalamus. This was recorded as the protection against the irreversible inhibition...
The p-aminophenethylamines (IV), (VI), and (VIII) are prepared from the compounds (I), (II), and (VII) as shown in the reaction scheme.doi:10.1002/chin.198716173FLORVALLL.FAGERVALLI.ASKA.-L.ROSSS.B.WILEY‐VCH Verlag GmbHChemInform...
Preparation of monoamine oxidase inhibitors Tobacco smoke preparations (tobacco particulate matter; TPM) were prepared as previously described (Lewis et al., 2012) using particulate matter collected from the smoke under ISO 3308 conditions (LabStat international, Kitchener, Canada). The tobacco and ciga...
Monoamine Oxidase B - Enzyme Inhibitors 目录项下的产品 14611-52-0 / MFCD00069299 R-(-)-Deprenyl Hydrochloride (R)-(-)-丙炔苯丙胺盐酸盐 原料 0 资源 0.0询 0.0%成交 交易量 试剂 103878-84-8 / MFCD20488051 Lazabemide hydrate 原料 0 资源 0.0询 0.0%成交 交易量 试剂 ...
Selective inhibitors of mono- amine oxidase type B and the ``cheese effect.'' Int Rev Neurobiol 100: 169-190, 2011.Finberg, J.P.M.; Gillman, K. Selective inhibitors of monoamine oxidase type B and the "cheese effect". In International Review of Neurobiology, Monoamine Oxidases and Their...