(redirected fromMonoamine oxidase inhibitors) Thesaurus Medical Encyclopedia monoamine oxidase inhibitor n.Abbr.MAOI Any of a class of antidepressant drugs that block the action of monoamine oxidase in the brain, thereby allowing the accumulation of monoamine neurotransmitters such as norepinephrine and sero...
Synonyms Monoamine oxidases; Inhibitors; Depressive illness; Parkinson's disease; Neuroprotection neurorescue Definition Ubiquitous mitochondrial monoamine oxidase [monoamine oxygen oxidoreductase (deaminating) (flavin‐containing); EC 1.4.3.4; MAO] exists in two forms, namely type A and type B [ ...
Themonoamine oxidaseinhibitors are an old-established class of antidepressant; their use is much more limited than the tricyclics because they are both less effective and more toxic. The antidepressant action of these drugs has been directly related to their main pharmacological action—the inhibiti...
Monoamine oxidase inhibitors (MAOIs) are the oldest class of antidepressants. Their mood-enhancing properties were discovered in the early 1950s when iproniazid, an antitubercular agent, was noted to improve patients' moods. The MAOIs can be categorized as hydrazine or nonhydrazine, re...
In order to understand how the wide variety of monoamine oxidase* inhibitors act on the enzyme it is first necessary to investigate the properties of the enzyme itself.doi:10.1007/978-1-349-01085-1_2K. F. TiptonMacmillan Education UKYOUDIM, M.B.H. , EDMONDSON, D. & TIPTON, K.F. (...
Revisiting monoamine oxidase inhibitors for the treatment of depressive disorders: A systematic review and network meta-analysis Background: Monoamine oxidase inhibitors (MAOIs) were the first class of modern antidepressants; however, they are under-utilized as compared to the newer ... R Suchting,...
The aim of this article is to synthesize informations about monoamine oxidase inhibitors drugs (MAOI) used in the treatment of depression. General informations on monoamine oxidase (MAO) and its kinetic properties are presented. MAO is an enzyme that degrades catecholamines and their 3-methoxy deriv...
Patent Update: Monoamine Oxidase InhibitorsPublication » Patent Update: Monoamine Oxidase Inhibitors.doi:10.1517/13543776.2.9.1421ShearerBarry G.Expert Opinion on Therapeutic Patents
a准确的设备选择,合理的布局设置,安全的系统设计应作为一名合格的工程师最基本的要求 The accurate equipment choice, the reasonable layout establishment, the safe system design should take a qualified engineer the most basic request[translate] aMonoamine oxidase inhibitors 单胺氧化酶抑制剂[translate]...
1. The principal routes of metabolism of the following monoamine oxidase inhibitors (MAOIs) are described: phenelzine, tranylcypromine, pargyline, deprenyl, moclobemide, and brofaromine. 2. Acetylation of phenelzine appears to be a minor metabolic pathway. Phenelzine is a substrate as well as an...