Use of the activated partial thromboplastin time for monitoring heparin therapy: Problems and possible solutionsThere is considerable variation in available methods for the activated partial thromboplastin time (APTT), giving widely differingresults with patients on heparin treatment. The study is primarily...
抗凝劑使用•抗凝血劑一般使用肝素(heparin)•活化凝血時間(Activatedclottingtime,ACT)大約控制在200-250秒之間•或aPTT控制在40-45秒之間•如果病人有高危險出血傾向,肝衰竭患者甚至可不必使用抗凝劑,可用前稀釋來減少透析器凝固。適應症(腎臟相關疾病)•急性腎衰竭合多重器官衰竭者併•急性腎衰竭合大量體液...
54, 55 Since theanticoagulant response to heparin varies among patients withthromboembolic disorders,56, 57, 58, 59, 60 it is standard practice toadjust the dose of heparin and monitor its effect by measurement of theAPTT that is sensitive to the inhibitory effects of heparin onthrombin, factor...
Successful use of the APTT in monitoring of the anti-factor Xa activity of the heparinoid organon 10172 in a case of HITS requiring open heart surgery 来自 NCBI 喜欢 0 阅读量: 19 作者:LR Marshall,PK Cannell,RP Herrmann 展开 摘要: PubMed comprises more than 22 million citations for ...
These calibrators were lyophilized human plasma containing a titrated quantity of heparin of 0, 0.38, 0.77, 1.14 and 1.50 IU/ mL respectively and were reconstituted with distilled water before each use. The heparin-free calibrator was also used as thinner of LMWH when preparing standard solutions....
aPTT/ACT/complete blood count (CBC)/Lab analysis. The experiment was repeated (a new device was attached and old one discarded) every hour for up to 6 h post-LPS infusion, allowing us to study and validate progression of coagulopathy in this animal model. Heparin therapy: the ...
for partial thromboplastin time (aPTT) measuring the anticoagulant effect of prolongation. Smart pump48sends infusion rate information to infusion monitor15and BPOC system44. Also aPTT test information received by Pharmacy information system29and BPOC system44and monitor15is compared with a current IV...
OBJECTIVE: To report a case of significant hepatic and renal failure with the use of argatroban in a patient with heparin-induced thrombocytopenia (HIT) re... WE Dager,RH White - 《Annals of Pharmacotherapy》 被引量: 75发表: 2003年 Argatroban During Percutaneous Transluminal Coronary Angioplasty...
Moreover, PT, ACT and APTT assays do not provide information on platelet function and therefore, do not serve as global coagulation tests. Because of the limitations of conventional blood clotting time tests, new point-of-care monitoring systems, such as thromboelastography (TEG) and rotation ...
Context.-Heparin contamination in blood samples may cause false prolongation of activated partial thromboplastin time (aPTT) and prothrombin time results. ... P Tientadakul,C Kongkan,W Chinswangwatanakul - 《Archives of Pathology & Laboratory Medicine》 被引量: 4发表: 2013年 Use of an automated...