Molecules and their functions in autophagy. Exp Mol Med. 2012;44(2):73-80.Pyo JO, Nah J, Jung YK. Molecules and their functions in autophagy. Exp Mol Med. 2012; 44 :73–80.J. Pyo, J. Nah and Y. Jung. "Molecules and their functions in autophagy", vol. 44, no. 2, pp. 73...
Molecules and their functions in autophagy. Autophagy is a self-degradation system of cellular components through an autophagosomal-lysosomal pathway. Over the last 15 yr, yeast genetic screens led t... J Ok,Pyo,Jihoon,... - 《Experimental & Molecular Medicine》 被引量: 206发表: 2012年 ...
Tumor suppressive functions include inhibition of cell proliferation, induction of apoptosis and regulation of autophagy. As tumors develop they switch their ... GJ Inman - 《Current Opinion in Genetics & Development》 被引量: 399发表: 2011年 FoxO Transcription Factors Promote Cardiomyocyte Survival up...
Here we reviewed and discussed the recent studies and discoveries related to the MHC-I molecules and their multidirectional functions in the development of cancer, mainly focusing on the interactions between MHC-I and the multiple participators in the tumor microenvironment and highlighting the ...
Mitophagy, a form of selective autophagy that removes damaged or dysfunctional mitochondria, plays a crucial role in maintaining mitochondrial and cellular homeostasis. Recent findings suggest that defective mitophagy is closely associated with various d
Tissue- and cell-specific localization of galectins, β-galactose-binding animal lectins, and their potential functions in health and disease Fifteen galectins,尾-galactose-binding animal lectins, are known to be distributed throughout the body. We herein summarize current knowledge on the tissue.....
Finally, functional enrichment analysis was performed for highly interacting (hub) genes using Enrichr and DAVID. The identification of hub genes shared among RA, OA, and PD, in addition to the analysis of their biological processes and pathways, may shed light on the molecular mechanism of the...
their survival, while others enhance or exploit this pathway to benefit their replication. The effect of viruses on autophagy may also sensitize cells to death or enhance cell survival and play a critical role in viral pathogenesis. In this article, we review the relationships between different ...
Pluripotency reprogramming and transdifferentiation induced by transcription factors can generate induced pluripotent stem cells, adult stem cells or specialized cells. However, the induction efficiency and the reintroduction of exogenous genes limit their translation into clinical applications. Small molecules th...
Mounting evidence suggests that the gut microbiome impacts brain development and function. Gut–brain connections may be mediated by an assortment of microbial molecules that are produced in the gastrointestinal tract, which can subsequently permeate many organs, including sometimes the brain. Studies in...