While strategies such as chemotherapy and immunotherapy have become the first-line standard therapies for patients with advanced or metastatic cancer, acquired resistance is still inevitable in most cases. The introduction of antibody‒drug conjugates
71. A molecular vacuum pump : Yu M Tuzankin , USSR patent no 276308, appl 29 th March 1969, publd 27 th Oct 1970doi:10.1016/0042-207X(72)91227-4SDOSVacuum
Early detection of eating disorders: a scoping review. Eat Weight Disord. 2022;27:21–68. Article PubMed Google Scholar Vieta E, Salagre E, Grande I, Carvalho AF, Fernandes BS, Berk M, et al. Early Intervention in Bipolar Disorder. Am J Psychiatry. 2018;175:411–26. Article PubMed ...
A substantial and diverse body of literature suggests that the pathophysiology of schizophrenia is related to deficits of bioenergetic function. While antipsychotics are an effective therapy for the management of positive psychotic symptoms, they are not efficacious for the complete schizophrenia symptom pro...
molecules Article Synthesis of High-Molecular-Weight Multifunctional Glycerol Polyhydroxyurethanes PHUs Bassam Nohra 1, Laure Candy 1, Jean-François Blanco 2, Yann Raoul 3 and Zéphirin Mouloungui 1,* 1 Laboratoire de Chimie Agro-industrielle (LCA), Université de Toulouse, INRA, INPT, ...
Profound weight loss induces reactive astrogliosis in the arcuate nucleus of obese mice Luke Harrison, Katrin Pfuhlmann, Sonja C. Schriever, Paul T. Pfluger June 2019 Abstract PDF Objective: Obesity has been linked to an inflammation like state in the hypothalamus, mainly characterized by reactiv...
Characterization of Cell Types Residing in the Adult SVZ NSCs formed a cluster in the center of the tSNE plot (Figure 2A). We identified them based on (1) their similarity to astrocytes (Doetsch et al., 1999); (2) the expression of Thbs4, which was previously reported to be highly en...
WT and En2−/− age-matched adult (3 to 5 months old; weight = 25 to 35 g) littermates mice of both sexes were used. Microarrays RNAs from dissected hippocampi and cerebella from three adult mice for each genotype were purified using standard column purification according to the ...
Leaf coloration in plants, attributed to anthocyanin compounds, plays a crucial role in various physiological functions, and also for pharmaceutical and horticultural uses. However, the molecular mechanisms governing leaf coloration and the physiological
Schizophrenia is a devastating psychiatric illness that detrimentally affects a significant portion of the worldwide population. Aging of schizophrenia patients is associated with reduced longevity, but the potential biological factors associated with aging in this population have not yet been investigated ...