British Journal of Cancer (2021) TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control Christopher H. Douse Iva A. Tchasovnikarova Yorgo Modis Nature Communications (2020)Sections Figures References Abstract Accession codes References Acknowledgements Author inform...
Article SRPK1‑siRNA suppresses K562 cell growth and induces apoptosis via the PARP‑caspase3 pathway Hailian Wang, Wei Ge, Wen Jiang, Dong Li, Xiuli Ju Pages: 2070-2076 Published online on: 13 十一月 2017 January-2018 Volume 17 Issue 1 Print ISSN: 1791-2997 Online ISSN: 1791-3004...
Journal of Ovarian Research (2023) 16:6 https://doi.org/10.1186/s13048-023-01094-5 Journal of Ovarian Research REVIEW Open Access Clinical application of PARP inhibitors in ovarian cancer: from molecular mechanisms to the current status Yongsong Wu1,2†, Shilin Xu2†, ...
High molecular weight compound combining camptothecins and anticancer effect enhancer and use thereofThe object of the present invention is to provide a polymer compound in which camptothecins and an anticancer effect enhancer, in particular, a PARP inhibitor, are bound to the same molecule. It is...
Vascular complications of diabetes pose a severe threat to human health. Prevention and treatment protocols based on a single vascular complication are no longer suitable for the long-term management of patients with diabetes. Diabetic panvascular diseas
Breast cancer, the most frequent female malignancy, is often curable when detected at an early stage. The treatment of metastatic breast cancer is more challenging and may be unresponsive to conventional therapy. Immunotherapy is crucial for treating met
Role of PARP inhibitors in cancer immunotherapy: potential friends to immune activating molecules and foes to immune checkpoints. Cancers (Basel). 2022;14(22):5633. Article CAS PubMed Google Scholar Marin-Acevedo JA, Withycombe BM, Kim Y, Brohl AS, Eroglu Z, Markowitz J, Tarhini AA, ...
Role of PARP inhibitors in cancer immunotherapy: potential friends to immune activating molecules and foes to immune checkpoints. Cancers (Basel). 2022;14(22):5633. Article CAS PubMed Google Scholar Marin-Acevedo JA, Withycombe BM, Kim Y, Brohl AS, Eroglu Z, Markowitz J, Tarhini AA, ...
Molecular weight masses are indicated in kDa Cell Death and Differentiation Regulation of PIDD by Hsp90 A Tinel et al 508 In order to determine the site of interaction between PIDD and Hsp90 in more detail, we expressed fragments of PIDD corresponding to the auto-cleavage products. ...
MUC1 is a highly glycosylated transmembrane protein with a high molecular weight. It plays a role in lubricating and protecting mucosal epithelium, participates in epithelial cell renewal and differentiation, and regulates cell adhesion, signal transduct