Palmitic acid (PA) is a saturated fatty acid commonly found in coconut oil and palm oil. It serves as an energy source for the body and plays a role in the structure and function of cell membranes. Beyond its industrial applications, PA has gained attention for its ...
Reprogramming of palmitic acid induced by dephosphorylation of ACOX1 promotes β-catenin palmitoylation to drive colorectal cancer progression. Cell Discov. 9(1), 26 (2023). Article CAS PubMed PubMed Central Google Scholar Rizzolo, D. et al. Bile acid homeostasis in female mice deficient in Cy...
Fabp2 and Fabp4 are fatty acid-binding proteins that facilitate intracellular transport of these FA, further explaining the elevated levels of FFAs such as palmitelaidic acid, palmitic acid, oleic acid, and cis-8,11,14,17-eicosatetraenoic acid in the liver. In addition, the significant up...
EtNP ethanolamine phosphate, FACS fluorescence-activated cell sorting, FSEC fluorescence-detection size exclusion chromatography, GlcN glucosamine, KO knockout, Man mannose, PI-PLC phosphatidylinositol-specific phospholipase C, PLM palmitic acid, TGP thermostable green fluorescence protein, TLC thin-layer ...
Fatty acid-binding proteins (FABPs), small cytosolic proteins that function in the uptake and utilization of fatty acids, have been extensively studied in higher vertebrates while invertebrates have received little attention despite similar nutritional requirements during periods of reproductive activity. Re...
Hypoxia-inducible factor 1-alpha (HIF-1α) regulates the expression of the ER stress marker GRP78 through a direct mechanism. It has been observed that overexpression of HIF-1α attenuated the palmitic acid-induced induction of GRP78, while knockdown of HIF-1α resulted in increased GRP78 exp...
(RSV) and non-typeable Haemophilus influenzae (NTHi)19,20. Another study reported a crucial regulatory role for EGFR in thrombin-mediated inflammation21. Furthermore, a study focusing on obesity-related cardiovascular diseases found that inhibiting EGFR reduced inflammation induced by palmitic acid in...
accordant with the situation thatV.sp. H4302 has the highest lipid content, implying that the FAS is not the rate-limiting process or not the dominant factor of the lipid accumulation inV.sp. H4302. The delta-9 desaturase (FAD9) catalyze the conversion of palmitic acid (C16:0) to POA....
This study analyzed the effects of various fatty acids on cancer cells and revealed that stearic acid, an abundant saturated fatty acid, had a stronger inhibitory effect on cell growth than did palmitic acid, which is also an abundant saturated fatty acid, by inducing DNA damage and apoptosis ...
N-acetyl-l-cysteine (NAC; A9165) and palmitic acid (P0500) were obtained from Sigma-Aldrich (St. Louis, MO, USA). AdipoRed assay reagent (#PT-7009) was obtained from Lonza (Basel, Switzerland). Cell proliferation assay Cells were seeded in 24-well plates (density: 2000 cells/well). ...