An isolated and purified nucleic acid molecule encoding high molecular weight protein (HMW) HMW3 or HMW4 of non-typeable Haemophilus is claimed having: a)\tthe DNA sequence SEQ ID No. 7 as shown in the specification and encoding protein HMW3 having the derived amino acid sequence of SEQ ...
Molecular cloning and characterization of the repetitive DNA sequences that comprise the constitutive heterochromatin of the A and B chromosomes of the Kor... (2012) Molecular cloning and characterization of the repetitive DNA sequences that comprise the constitutive heterochromatin of the W chromosomes...
1. Enter theRNAsequence. 2. Press calculate to display the molecular weight. Data Entry 5' hydroxyl5' phosphate5' triphosphate Calculate Feedback Submit request References This online tool may be cited as follows MLA "QuestCalculate™RNA Molecular Weight Calculator."AAT Bioquest, Inc.,6Dec.2024...
Short-read metagenomic sequencing and de novo genome assembly of the human gut microbiome can yield draft bacterial genomes without isolation and culture. However, bacterial genomes assembled from short-read sequencing are often fragmented. Furthermore, these metagenome-assembled genomes often exclude repea...
Nearly 97% of the human genome is non-coding DNA, and introns occupy most of it around the gene-coding regions. Numerous intronic sequences have been recen... SY Ying,SL Lin - 《Methods Mol Biol》 被引量: 120发表: 2009年 Mutations of SPG4 are responsible for a loss of function of...
Biochemical and structural studies of the human MCM replicative DNA helicase complex show differences from the yeast complex and provide insights into mechanisms of double hexamer assembly on sequence-independent replication origins. Florian Weissmann ...
Evo: DNA foundation modeling from molecular to genome scaleEvo is a biological foundation model capable of long-context modeling and design. Evo uses the StripedHyena architecture to enable modeling of sequences at a single-nucleotide, byte-level resolution with near-linear scaling of compute and ...
Molecular mechanisms of DNA damage Genomic instability manifests as permanent and transmissible changes in DNA sequence [13,41]. DNA damage caused by an inherently unstable genome includes spontaneous deamination, hydrolysis, and many other chemical changes such as different types of breaks, changes in...
Altering traits and fates of wild populations with Mendelian DNA sequence modifying Allele Sails Population-scale genome modification can alter the composition or fate of wild populations. Here the authors introduce Allele Sails as a method for spreading genetic changes throughout a population. ...
Understanding how cis-regulatory function is encoded in DNA sequence using massively parallel reporter assays and designed sequences. Genomics 106, 165–170 (2015). CAS PubMed Google Scholar Fuqua, T. et al. Dense and pleiotropic regulatory information in a developmental enhancer. Nature https:/...