The upfront use of a moderate-intensity statin plus ezetimibe may improve LDL-C control and lead to the prevention of CVD in real-world settings.Li, ShaCardiometabolic Center, State Key Laboratory of Cardiovascular Disease, FuWai Hospital, National Center for Cardiovascular Diseases, Chinese Academy...
Odds ratios for specific components of the composite cardiovascular end point are provided in Table 3, showing similar associations between intensive statin therapy and each cardiovascular end point component. Intensive-dose therapy was not associated with lower all-cause mortality compared with moderate-...
For patients receiving a high-intensity statin, evolocumab administered every 2 weeks reduced LDL-C values from a baseline mean of 89 to 94 mg/dL to an on-treatment mean of 35 to 38 mg/dL, and 94% achieved an LDL-C value less than 70 mg/dL (Table 2; eTables 3 and 4 in Suppleme...
Quality-of-life scores improved only in symptomatic statin users following exercise training (P < 0.01). Conclusions A moderate intensity endurance and resistance exercise training program improves muscle performance, capillarization, and mitochondrial content in both asymptomatic and symptomatic statin users...
Despite the appeal of this approach, because it could be easily implemented in a comprehensive MDCT protocol without increase of patient risks, it is possible that CTDE could be optimized using different parameters—namely higher tube current and current intensity or dedicated injections of higher ...
Recentlymoreattention has been paid to the paradoxical intensity of thisindirect relationship. GeorgCavallar,inarecent bookaboutKantian cosmopoli-tanism, relates that he wasvery surprised to discover that,inregardsto hospital-ity and cosmopolitanism, Diderot was so close toKant,despite the fact that“...
Recent studies such as the RACING trial suggest that the combination of moderate-intensity statins and ezetimibe (MIS+EZE) may achieve a greater LDL cholesterol reduction and a lower adverse event rate than high-intensity statins alone (HIS) [2]. PURPOSE. The aim of this systematic review and...
The long-term outcome of first-line moderate-intensity statin with ezetimibe combination therapy for secondary prevention after percutaneous coronary intervention in patients with acute coronary syndrome (ACS) compared to high-intensity statin monotherapy remains elusive. The objective ...
http://www.ncbi.nlm.nih.gov/htbin-post/Entrez/query?db=m&form=6&Dopt=r&uid=entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8484829&dopt=AbstractGoogle Scholar High-Intensity Statin Treatment for Coronary Heart Disease JAMA Editorial March 3, 2004 See More About Cardiology Dyslipidemia ...
AIMS. To compare the effects of moderate-intensity statin plus ezetimibe combination therapy to high-intensity statin monotherapy based on baseline low-density lipoprotein cholesterol (LDL-C) levels. METHODS AND RESULTS. In the RACING trial, 3780 atherosclerotic cardiovascular disease (ASCVD) patients ...