In vitro and in vivo studies from our group and others, conducted in models of colon, head and neck and breast cancers, showed that treatment with HDACi is associated with the downregulation of thymidylate synthase (TS), the key enzyme in the mechanism of action of 5-Fluorouracil (5-FU) ...
The reduced group size is explained by missing fecal samples. We analyzed the composition of the gut microbiota and found significant differences in the abundance of bacterial strains at the family level. While the abundance of Bacteroidaceae, Bifidobacteroidaceae, Streptococcaceae, and Ruminococc...
In vitro and in vivo studies from our group and others, conducted in models of colon, head and neck and breast cancers, showed that treatment with HDACi is associated with the downregulation of thymidylate synthase (TS), the key enzyme in the mechanism of action of 5-Fluorouracil (5-FU) ...