In this chapter, we shall describe the fundamental modeling with the birth-death stochastic process. The idea and concept in such a modeling is very important to understand the meaning of modeling about the deterministic mathematical model which superficially seems not to have any relation to the ...
representation- an activity that stands as an equivalent of something or results in an equivalent simulation- the act of imitating the behavior of some situation or some process by means of something suitably analogous (especially for the purpose of study or personnel training) ...
as it was a step to dismantling the powerful New Deal coalition. Even at the time, there was something awkward about the ejection of communist from the Democratic party, in that the liberals who were doing the ejection seemed to be in accord with right-wing...
For example, normal urethral development in male embryos requires closure and separation of the urethral plate endoderm from the overlying ectoderm on the ventral surface of the GT. This process is linked to sexually-dimorphic patterns of programmed cell death (apoptosis) and the local regulation of...
Human embryonic stem cell-derived cardiomyocytes (hESC-CMs) have been reported to exhibit immature embryonic or fetal cardiomyocyte-like phenotypes. To enhance the maturation of hESC-CMs, we identified a natural steroidal alkaloid, tomatidine, as a new s
Importantly, targeted inhibition of the check-point inhibitor CHK1 with MK-8776 effectively caused death of p21-high T47D cells, thus establishing a new vulnerability of BYL719-resistant breast cancer cells. Together, our integrated studies uncover hidden molecular mediators causing resistance to PI3K...
Infibulation (also called Pharoanic circumcision). The vaginal opening is reduced by removing all or parts of the external genitalia (the clitoris, labia minora, and labia majora) and sewing, pinning, or otherwise causing the remaining tissue to fuse together during the healing process. Those pr...
(E8.5). By E9, melanoblasts are primarily localized in the head and face, with fewer in cervical and trunk regions (Fig.1B) [24,25,26]. At E10.5, they enter the dorso-lateral pathway and begin to differentiate into melanocytes, a process regulated by WNT signaling [27]. The ...
Main Outcomes and Measures Process outcomes included VHA scheduled, completed, and missed appointments; mental health visits; and safety plan documentation and documentation within 6 months for individuals without plans within the prior 2 years. Clinical outcomes included mental health admissions, emergency...
Elimination of mother-to-child transmission of HIV and Syphilis (EMTCT): process, progress, and program integration PLoS Med, 14 (6) (2017), Article e1002329 Google Scholar 21 S. Nesheim, A. Taylor, M.A. Lampe, P.H. Kilmarx, L. Fitz Harris, S. Whitmore, et al. A framework for...