Amphotericin B and its new derivatives - mode of action. Curr Drug Metab 2009; 10(5): 459-69Baginski M, Czub J (2009) Amphotericin B and its new derivatives: mode of action. Curr Drug Metab 10:459–469Baginski M, Czub J. Amphotericin B and its new derivatives - mode of action....
Amphotericin B (AmB) is a very effective anti-fungal polyene macrolide antibiotic whose usage is limited by its toxicity. Lack of a complete understanding ... Baginski,Maciej,Resat,... - BBA - Biomembranes 被引量: 146发表: 2002年 Theoretical study of the complexation of amphotericin B with...
Combination of the MSE with the well-known commercial antifungal drugs amphotericin B (Amp B), nystatin (NYS) and fluconazole (FLC) resulted in the killing of C.glabrata at non-inhibitory concentrations, i.e., 0.35μg/mL for Amp B, 0.55μg/mL for NYS and 1.19μg/mL for FLC. Notably...
Helmerhorst EJ, Reijnders IM, van’t Hof W, Simoons-Smit I, Veerman EC, Amerongen AV (1999) Amphotericin B- and fluconazole-resistant Candida spp.,Aspergillus fumigatus, and other newly emerging pathogenic fungi are susceptible to basic antifungal peptides. Antimicrob Agents Chemother 43:702–70...
Subcutaneous infection with Phialophora richardsiae and its susceptibility to 5-fluorocytosine, amphotericin B and miconazole Two patients are described with subcutaneous infections due to Phialophora richardsiae. Both were diabetics and originally came from subtropical areas. One... ML Corrado,I Weitzm...
Coexistence of domains with distinct order and polarity in fluid bacterial membranes Photochem. Photobiol., 76 (2002), pp. 1-11 Google Scholar [32] K.C. Gray, D.S. Palacios, I. Dailey, M.M. Endo, B.E. Uno, B.C. Wilcock, M.D. Burke Amphotericin primarily kills yeast by simply ...
Selectivity index (SI) of Jelleine-I is at least 4.6 times higher than amphotericin B. Jelleine-I could increase the production of cellular ROS and bind with genome DNA. This may contribute to its antifungal activity. Furthermore, drug resistance is not induced when the fungal cells were ...
41 Doft B S , Weiskoff J , Nillsson-Ehle I , Wingard LB : Amphotericin clearance in vitrectomised versus non-vitrectomised eyes. Ophthalmology 1985 , 92: 1601-5 . 42 Laurent TC , Bjork I; Pietruszkiewicz A et al. : On the interaction between polysaccharides and other ...
Proffit RT,Adler-Moore J,Fujii G.Stability and mode of action of AmBisome (liposomal amphotericin B)[J].1994,28(1-3).Stability and Mode of Action of Ambisome (Liposomal Amphoteri cia B). Proffitt R T,Adler -Moore J,Fujii G,et al. Journal of Controlled Release . 1994...
The mechanism of penetration of compounds into the Candida cells is not yet clear. A natural pure compound, obliquumol isolated from P. obliquum (patented in SA, USA and Europe) had better antifungal action against C. albicans and was less cytotoxic than the positive control, Amphotericin.C....