Analysis of HBV cccDNA Minichromosome Accessibility by MNase-qPCR and High-Throughput Sequencingdoi:10.1007/978-1-0716-4027-2_4The covalently closed circular DNA (cccDNA) of the hepatitis B virus (HBV) is organized as a minichromosome structure in the nucleus of infected hepatocytes and considered ...