This could reflect more older siblings having been diagnosed with ASD between the younger siblings’ recommended ages of first- and second-dose administration, potentially leading parents to raise de novo concerns about the vaccine’s safety at the time second dose decisions are being made. This ...
Multifunctional nanosonosensitizers generally comprise organic/inorganic sonosensitizers for ROS generation, reformative molecules for improved BBB permeability, tumor-specific agents for identification of precise tumor location, and metal ions for enhanced magnetic reso- nance imaging (MRI). Physical methods...
Vaccine. 2009;27:369–374. CAS PubMed Google Scholar Darcissac ECA, Vidal V, Guillaume M, Thebault JJ, Bahr GM. Clinical tolerance and profile of cytokine induction in healthy volunteers following the simultaneous administration of IFN-α and the synthetic immunomodulator murabutide. J ...
Mediating mitochondrial fission is the classical and primary function of Drp1 in ischemia and hypoxia. The traditional understanding of mitochondrial fission process can be summarized as follows. First, the mitochondrial nucleoid formed by replicating mtDNA determines the location of ER recruitment on the ...
accumulation, many strategies have been developed to improve the efficacy of SDT for GBM treatment, including improved BBB penetration for sonosensitizers, enhanced tumor-targeted sonosensitizer accumulation, and identification of precise tumor location, which is generally referred to as imaging—guided ...
A successfully designed for BNBMs thus has to fit the mechanical requirements of the implant location and their cellular microenvironment. Through the intensive study of the mechanical characteristics of native ECM in different tissues, researchers gradually began to explore the biomimetic biomechanical ...