The dosage for MMR vaccine is 0.5 mL by the subcutaneous route. If a second dose is indicated, the minimum interval between the first and second doses should be separated by at least 4 weeks (28 days). The preferred injection site for adults isthe posterior triceps aspect of the upper ar...
Complete information on the schedule, doses and route of administration was available for five studies [5,20,22,23,26]. Five recent studies reported definitions for all adverse events monitored [29–33], three of these were single event- specific studies [30,31,33]. Five studies had no ...
The court had ruled 13 months ago that a combination of the measles-mumps-rubella vaccine, commonly known as the MMR vaccine, and thimerosal does not cause the disorder, so the new ruling may finally close the bulk of litigation on the matter. The earlier ruling has been appealed to the U...
Children were eligible if they were 34–44 months old, had received 1 dose of MMR between 11 and 20 months of age (the administration of the first dose of MMR vaccine in Finland was recommended at 14–18 months of age until 2011, when it was lowered to 12 months), and had not … ...
If so, then the aerosol route might improve the poor primary immune responses to injected Rubini strain, which has been especially evident with ELISA antibody studies [26,27], and potentially help correct the low effectiveness of this safe vaccine in preventing mumps, considering that aseptic ...
The study patients were regularly followed at the study center and no serious or relevant adverse events were recorded in the medical charts after the MMR vaccine administration. For each whole-blood sample, the levels of IgG were within the normal range (7–16 mg/mL) and the mean value was...
while others might remain unresponsive even after administration of the standard number of doses. Therefore, prediction of vaccine efficiency before the administration of the vaccine to any particular individual might be useful for health and economic reasons. Individuals deemed to be unresponsive by vac...
Drug delivery systems (DDS) have recently emerged as a promising approach for the unique advantages of drug protection and targeted delivery. However, the access of nanoparticles/drugs to the central nervous system (CNS) remains a challenge mainly due to the obstruction from brain barriers. Immune...
Immune checkpoint blockade (ICB) therapy for cancer has achieved great success both in clinical results and on the market. At the same time, success drives more attention from scientists to improve it. However, only a small portion of patients are respon
The present study was conducted to evaluate the antibody responses and tolerability of the MMR vaccine delivered by aerosol compared with the traditional subcutaneous route in a group of adult volunteers. Most adults were deemed likely to have antibodies against the three vaccine viruses, naturally acq...