Matrix Metalloproteinases (MMPs) and their regulators – Tissue Inhibitors of Matrix Metalloproteinases (TIMPs) – participate in extracellular matrix remodeling, fibrosis, and semen liquefaction, as well as to inflammatory activity. Seminal plasma has been shown to contain MMPs (MMP-2 and MMP-9) an...
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nucleatum in our own transcriptome data using the C5 gene sets of MSigDB website. The significant terms of GSEA were visualized using the R package “enrichplot”. Correlation analysis The Pearson correlation analysis was performed with “ggpubr” package and visualized using “ggplot2” package....
Results MMP13 rs2252070 is associated with ESCC risk in Chinese Han populations. No Significant dif- ferences were found between cases and controls for both case-control sets in terms of median age and sex distri- bution (both P > 0.05). This indicated that the frequency ...
Results: TT genotype in MMP9 T-1702A was more frequent in sarcoidosis (p<0.0001, OR=13.71, 95% CI 7.02–26.80) and resulted in higher expression of MMP9 mRNA (p<0.0001). No differences were found between TT and AT/AA patients in terms of radiological stage, lung function test parameter...
Gursoy and collaborators [22] indicated higher MMP-8 levels in pregnancy and lower ones in the postpartum period, while Erhles and collaborators [23] found no significant difference between pregnant women and those without any pregnancy in terms of their MMP-8 levels. Research that addresses the...
Department of Oral and Maxillofacial Surgery, Center for Medical Biotechnology, University Hospital Regensburg, 93053 Regensburg, Germany 3 Experimental Orthopaedics, Centre for Medical Biotechnology (ZMB), Bio Park 1, University of Regensburg, 93053 Regensburg, Germany ...
While MMP-9 is mostly upregulated in inflammatory terms, MMP-2 is constitutively expressed in the brain [33]. Brain inflammation is initiated and sustained by lymphocyte migration across the BBB [34]. Animal models proved that MMP-2 and MMP-9 are the key elements in the induction of neuro...
in terms of various biochemical, molecular, and histological parameters. We observed a significant recovery in the wound area. Increased levels of MMP-2, 9, 14, TIMP-2, VEGF-A, and VEGF-R1 were induced by naringin in the HaCaT cells. The time course experiments further revealed that levels...