混合性结缔组织病(Mixed connective tissue disease,MCTD) 流行病学:可发生于任何年龄,30-50岁多发。多数患者为女性,男女之比为1:7。小样本调查提示混合性结缔组织病的发病率约10/10000. 临床表现:雷诺现象、双手肿胀、多关节痛或关节炎、...
Few patients experience a stable disease course without maintenance treatment, but those who do must be identified before maintenance treatment is started. If muscle strength and function deteriorate in the weeks ...
Clinically MMN is a pure motor neuropathy, which as such can mimic motor neuron disease. GM1-specific IgM antibodies are present in the serum of approximately half of all MMN patients, and are thought to play a key role in the immune pathophysiology. Intravenous immunoglobulin (IVIg) treatment ...
The earlier MMN is diagnosed, the sooner you can begin treatment to manage this progressive disease. Build your guide How is MMN diagnosed? Usually, when people start to notice MMN symptoms, they think it’s probably temporary or related to an activity in their life. For instance, it wou...
treatment [35,43,59,60,73]. However, it may be important to understand how treatment (or tinnitus being non-bothersome) may alter MMN amplitudes, because two studies, in which two different types of tinnitus treatment were used, showed that MMN amplitudes in response to frequency deviants in...
Multifocal motor neuropathy, or MMN, is a rare disorder in which multiple motor nerves are attacked by one’s own immune system, causing muscle weakness that can worsen over time. MMN is a slowly progressive disease that commonly affects one side of the body (asymmetric) and commonly begins ...
Objective:To investigate the effects of the tests ofmismatch negativity(MMN)and prefrontal cognitive function on the evaluation of cognitive function in patients with Parkinson's disease(PD)and their clinical value. 目的:探讨失匹配负波(MMN)与额叶认知功能测试在评价Parkinson病(PD)患者认知功能中的作用及...
None of the participants had hearing impairments, history of neurological disease, or musical training more than 2 years besides regular school lessons (according to self-report). All participants were compensated (200 NOK, approx. 20 EUR) at the end of the experiment. The study was carried ...
Adjunctive treatment of MMN patients with MMF at a dose of 1 g twice daily is safe but does not alter disease course or allow significant reduction of IVIg doses. 展开 关键词: multifocal motor neuropathy immune-mediated neuropathy immunosuppressant treatment immunoglobulins DOI: 10.1093/brain/awm...
Multifocal motor neuropathy (MMN) is a unique disease mimicking motor neuron disease, but it is treatable with intravenous immunoglobulins. Anti-GM1 IgM an... R Kaji - 《Current Treatment Options in Neurology》 被引量: 16发表: 2008年 Rasch-built Overall Disability Scale for Multifocal motor neur...