Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND), is a rare neurodegenerative disease. Approximately 5% to 7% of ALS/MND patients report a family history of a similarly affected relative. Superoxide dismutase-1 gene mutations are the cause in about 20% of familial ...
muscles twitching, pain in the body, difficulty in swallowing, etc. Physiotherapy is found to be very useful for controlling disease progression. Regular physiotherapy sessions can improve muscle tones, flexibility, and power. This in turn helps the patients of MND to improve their quality of life...
Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease or motor neuron disease (MND), is a rapidly progressive and fatal neurological disease. It was first diagnosed in 1874 by French neurologist Jean-Martin Charcot but despite more than 140 years of research, there is still...
Living With a Motor Neuron Disease The outlook is different for each type of motor neuron disease. Some are milder and progress more slowly than others. Although there is no cure for motor neuron diseases, medicines and therapy can ease symptoms and improve your quality of life. SourcesUpdate ...
making them ineffective for treatment. This is because: 1)Adult stem cells from the patient's own body already possess the same genetic defects as the disease, rendering them ineffective for treatment, and 2) Adult stem cells have a shorter lifespan and are not suitable for treating chronic ...
The premise of polyclonal Tregs for adoptive cell therapy, as tested in two type 1 diabetes trials [16, 17], depends on the natural existence of rare, disease-relevant TCRs in the cell population. As such, numerous studies in NOD mice have demonstrated that therapy using antigen-specific ...
Ebselen provides a promising new avenue for treatment of MND - An international study led by biochemists has shown that the drug-molecule ebselen can correct many of the toxic characteristics of a protein that causes some cases of hereditary motor neuron
targets for treating neurological diseases, including Alzheimer’s disease (AD), Huntington’s disease (HD), Parkinson’s disease (PD), multiple sclerosis (MS), Rett syndrome (RS), developmental and epileptic encephalopathies (DEE), and motor neuron disease/amyotrophic lateral sclerosis (MND/ALS)...
In an aspect of the invention there is provided a protease or composition of the invention for use in the treatment of an immune dysregulation disorder or disease. In an embodiment, the immune dysregulation disorder is selected from the group comprising asthma, eczema, inflammatory bowel disease, ...
An international study led by biochemists at the University of Liverpool has shown that the drug-molecule ebselen can correct many of the toxic characteristics of a protein that causes some cases of hereditary motor neurone disease (MND).