1.2 药品与试剂 MK-2206 粉末(美国 Selleck Chemicals 公司,批号:S1078, 纯度:99%);RPMI 1640 培养基和胎牛血清(美国 Gibco 公司);MTT(美国 Sigma 公司分装,批号:M2128);膜联蛋白Ⅴ (Annexin Ⅴ)-异硫氰酸荧光素(FITC)细胞凋亡检测试剂盒 (南京凯基生物有限公司,批号:KGA107);ECL 化学发光检测 试剂盒(...
(PDAC). The application of inhibitors against PI3K and AKT has been considered as a therapeutic option. We investigated PDAC cell lines exposed to increasing concentrations of MK-2206 (an AKT1/2/3 inhibitor) and Buparlisib (a pan-PI3K inhibitor). Cell proliferation, metabolic activity, biomass...