Cell division is the process that cells use to duplicate themselves. There are two main types of cell division: mitosis andmeiosis. Mitosis is the process that cells use to duplicate themselves for growth and repair. Meiosis is the process that cells use to create gametes, such as sperm and ...
When a cell starts to divide, it forms a spindle, a micro-machine made of microtubules, which separates the duplicated chromosomes. The attachment of microtubules to chromosomes is mediated by kinetochores, protein complexes on the chromosome. Spindle microtubules can be divided into three major clas...
Two types of cell division are known for eukaryotic organisms: mitotic and meiotic. Recombination takes place in both. In cells that enter meiosis, the chromosomes have already undergone DNA replication so that each chromosome consists of two sister chromatids connected by a shared centromere. During...
Precise coordination of cell cycle progression is critical not only for normal cell division but also under conditions of stress leading to DNA damage or incomplete DNA synthesis. Deregulation of cell cycle control has been shown to be a leading cause of genetic instability in human cancers (1, ...
The following sections are included:IntroductionDescription of Spindle BirefringenceChanges in Birefringence during MitosisMotion Picture of Living Cells in DivisionEffect of Low TemperatureThermodynamic StudiesOrienting Centers—Ultraviolet Microbeam ExperimentsConclusionREFERENCESDISCUSSION Introduction Description of ...
The mitotic checkpoint is a specialized signal transduction pathway that contributes to the fidelity of chromosome segregation. The signaling of the checkpoint originates from defective kinetochore-microtubule interactions and leads to formation of the m
g, Time-lapse microscopy of NADPH dynamics with iNap1 during HeLa cell division after the treatment of RO3306 and Compound C. Images were pseudo-colored by F425/F485. Scale bar, 10 μm (left). Relative ratios of iNap1 signal at time point 40 mins (metaphase) to the signal at 0...
This indicates that SP cell specification might rely both on mitotic and postmitotic COUP-TFI function. Finally, ROR expression, which regulates barrel formation on innervation of layer IV neurons by TCA37 (Fig. 1c), and serotonin, a neurotransmitter labelling TCAs in primary sensory areas, ...
In previous studies, we have described the structure of an extra-chromosomal gene delivery system, which is able to establish stable cell clones and provide prolonged gene expression over at least 100 cell division cycles and in the absence of selection pressure [19]. Established cell clones have...
Alternatively, as it has been suggested recently for MyoD [13], such a mechanism could allow a low amount of Myf5 to be preserved during passage through mitosis, in order for the cell to be able to mobilize it immediately after completion of cell division....