MKP-1 (also called externally regulatedphosphataseor CL100) is a dualspecificitymitogen-activated protein kinasephosphatase encoded by an immediate-early gene (seeSection II, A, 2). Transfected NIH 3T3 cells that express MKP-1 in a constitutive manner show a significant decrease in growth rate co...
Key Words: Mitogen-activated protein kinase; p38-regulated/activated protein kinase; Extracellular signal-regulated kinase; Protein kinase A; Subcellular localization; Phosphorylation; Protein interaction Citation: Kostenko S, Dumitriu G, Lægreid KJ, Moens U. Physiological roles of mitogen-activated-...
Sakaguchi, S., et al., “Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanisms of self-tolerance causes various autoimmune diseases,” J Immunol Aug. 1, 1995;155(3):1151-64. Seddon, B. and Mason, D.,...