Effects of mitochondrial complex-I inhibition on the protein expression of ENaC subunits in obstructed kidneys. We further examined the protein levels of the collecting duct sodium channels ENaCα , ENaCβ , and ENaCγ . Similar to NKCC2, downregulation of ENaCα was reversed by ...
Mammalian respiratory complex I (CI) is a 45-subunit, redox-driven proton pump that generates an electrochemical gradient across the mitochondrial inner membrane to power ATP synthesis in mitochondria. In the present study, we report cryo-electron microscopy structures of CI fromSus scrofain six tre...
Mitochondrial complex III stabilizes complex I in the absence of NDUFS4 to provide partial activity Complex I (CI, NADH ubiquinone oxidoreductase), the largest complex of the respiratory chain, is composed of 45 structural subunits, 7 of which are encoded... Calvaruso,A M.,Oliver,... - 《...
Subunits of Mitochondrial Complex I Exist as Part of Matrix- and Membrane-associated Subcomplexes in Living Cells Mitochondrial complex I (CI) is a large assembly of 45 different subunits, and defects in its biogenesis are the most frequent cause of mitochondrial disor... CEJ Dieteren,PHGM Will...
The electrophoretic pattern of the liver preparation showed the presence of 11 subunits, with apparent molecular weights identical to the ones reported for the heart complex. Western blot analysis and isoelectric focusing followed by two-dimensional gels of bc 1 complexes from liver and heart were ...
58 Consistent with these studies, our data showed that GMFG knockdown in macrophages induced the iron deficiency response; reduced expression of mitochondrial complex I (NDUFV2) and complex II (SDHD) subunits, ISCU, and the antioxidants SOD2 and SOD1; and moderately increased mtROS production....
An analysis of the secondary structure of proteins for 250 fish species (248 ray-finned and 2 cartilaginous fishes) illustrated that cytochrome c oxidase subunits (COI, COII, and COIII) and a cytochrome bc1 complex subunit (Cyt b) had substantial amino acid conservation. Among the four ...
The mitochondrial protein import complex is a set of multisubunit protein complexes that recognize and transport mitochondrial proteins to their functional location (Schulz et al., 2015). From: International Review of Cell and Molecular Biology, 2017 ...
which helped the cells functional oxygen consumption and respiration. In addition, mitochondrial transfer helped ρ0 cells restore their cellular behaviour, including nonadherent proliferation, aerobic viability, and OXPHOS dependent cellular motility [83]. Moreover, ETC complex V-inhibitor-sensitive ATP ...
Systematic expression analysis of the mitochondrial complex III subunits identifies UQCRC1 as biomarker in clear cell renal cell carcinomadoi:10.1016/s1569-9056(17)31035-7J. EllingerA. GromesM. PossM. BrüggemannD. SchmditN. EllingerY. Tolkach...