Mitochondria in the Pulmonary Vasculature in Health and Disease: Oxygen-Sensing, Metabolism, and DynamicsIn lung vascular cells, mitochondria serve a canonical metabolic role, governing energy homeostasis. In addition, mitochondria exist in dynamic networks, which serve noncanonical functions, including ...
D. Mitochondria in vascular health and disease. Annu. Rev. Physiol. 75, 95–126 (2013). Article CAS PubMed Google Scholar Pernas, L. & Scorrano, L. Mito-morphosis: mitochondrial fusion, fission, and cristae remodeling as key mediators of cellular function. Annu. Rev. Physiol. 78, 505...
Mitochondria in vascular disease Mitochondria are often regarded as the powerhouse of the cell by generating the ultimate energy transfer molecule, ATP, which is required for a multitude o... Emma Yu, John Mercer and Martin Bennett* - 《Cardiovascular Research》 被引量: 157发表: 2012年 Oxidative...
Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease. Nat. Rev. Clin. Oncol. 13, 674–690 (2016). Article CAS PubMed PubMed Central Google Scholar Lynce, F. & Nunes, R. Role of platinums in triple-negative breast cancer. Curr. Oncol. Rep. 23, 50 (...
Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease. Nat. Rev. Clin. Oncol. 13, 674–690 (2016). Article CAS PubMed PubMed Central Google Scholar Lynce, F. & Nunes, R. Role of platinums in triple-negative breast cancer. Curr. Oncol. Rep. 23, 50 (...
Iron overload is a pathological condition characterized by the abnormal accumulation of iron within the body, which may result from excessive iron intake, disorders of iron metabolism, or specific disease states. This condition can lead to significant health complications and may pose life-threatening...
Among these, kidney disease exhibits the strongest association with mortality in individuals with diabetes, more so than other vascular complications.1 This is because the kidneys are particularly prone to diabetic vascular complications due to their intensive metabolic demands. DKD manifests through the...
Cardiovascular disease (CVD) remains a global economic burden even in the 21st century with 85% of deaths resulting from heart attacks. Despite efforts in reducing the risk factors, and enhancing pharmacotherapeutic strategies, challenges persist in early identification of disease progression and function...
Mitochondrial dynamics in health and disease: mechanisms and potential targets Article Open access 06 September 2023 References Marieb, E. & Hoehn, K. Essentials of Human Anatomy & Physiology (Pearson Education, 2022). Picard, M. & Shirihai, O. S. Mitochondrial signal transduction. Cell Metab...
disorders in different organ systems. In this regard, fresh insights into the interplay between mitochondria and PCD are expected to be inspired in disease treatment development in contexts ranging from in vitro to preclinical and clinical trials. PCD Programmed cell death, EMR Electronic medical ...