鉴于此,西南大学李原芳教授、黄承志教授团队提出了一种以锌基金属有机框架(Zn-MOFs)为单发光体构建了用于miRNA-133a检测的无共反应剂的比率ECL传感器。该项工作发表在Analytical Chemistry上。 图1. Zn-MOFs的合成(A)以及miRNA-133a检测的无共反应剂的比率ECL生物传感器示意图。 研究表明,作者所制备的Zn-MOFs具有...
MicroRNA (miRNA) plays an important role in immune cell activation, inflammatory cytokine release and immune response. However, the mechanism of miR-133a in sepsis remains largely unknown. Methods Sepsis mice models were established by applying the cecal ligation and puncture (CLP) method. ...
插画 关于 微核糖核酸(miRNA,有miR133a)结构,计算机模型 MiRNA是在几种疾病有基因管理作用并且扮演作用的非编制程序核糖核酸 通过部分地透明单色分子表面,核糖核酸的丝带表示法能看. 插画 包括有 编码, 核酸, 放音器 - 48132649
食管鳞状细胞癌组织中hsa-miRNA-133a的表达变化及意义
miRNA-133a对心肌缺血再灌注损伤后心室重构的保护作用及其机制研究 目的:缺血性心脏病经介入及手术治疗后,心外膜冠状动脉的再通并不意味着完全心肌再灌注的实现及正常机体内环境的恢复,缺血再灌注后仍然存在着严重的心肌损害一心室重构... 薛才广 - 《天津医科大学》 被引量: 8发表: 2013年 微小RNA-133a在心肌...
Osteoporosis is a chronic disease characterized by bone fragility that results in fractures and a variety of miRNAs are involved in osteoclast differentiation therefore, the current case control study aimed to estimate miRNA-133a and miRNA-25 3p in osteoporotic patients and evaluate relationship of the...
和肝癌细胞中肿瘤相关miRNA表达谱,发现miR-133a在肝癌细胞中低表达.miR-133a在多种恶性肿瘤中起负性调控作用,但其在HCC的发生发展中的作用及其机制如何则未见报道.因此本研究拟从三方面对miR-133a在HCC中的作用进行研究:一,通过分析miR-133a在肝癌组织和正常组织中的表达情况,研究miR-133a与HCC发生,发展的相关...
Fig. 1. . The influences of miRNA-324/133a analogues on the recruitment and functional state of associative memory cells in the barrel cortex (A) miRNA analogues were injected into the barrel cortex (BC) before the training, and single-unite recordings were performed in the BC after the tra...
Collectively, miRNA-133a is involved in the regulation of postmenopausal osteoporosis through promoting osteoclast differentiation. 展开 关键词: miRNA-133a postmenopausal osteoporosis osteoclast differentiation DOI: 10.1093/abbs/gmy006 被引量: 8 年份: 2018 ...
目的 观察上调miRNA-133a表达是否可改善缺血再灌注损伤后心肌损害及心脏功能.方法 建立活体大鼠心肌缺血再灌注损伤模型.将实验动物随机分为5组:(1)空白对照组(Sham组);(2)缺血再灌注损伤组(I/R组);(3)缺血再灌注损伤+miRNA-133a模拟物agomiR-133a组(I/R+ agomiR-133a组);(4)缺血再灌注损伤+阴性对照序列...