The inhibition of miR-146b-5p in PCCl3 also inhibited migration and invasion, and additional (exogenous) overexpression of this miR in TPC-1 and BCPAP cells increased migration and invasion, without effects on cell morphology or gelatin degradation. The overexpression of SMAD4 in BCPAP cells, ...
Moreover, miRNA-146b-5p overexpression had inhibitory effects on myotube differentiation in pCM cells.#Collectively these results demonstrate that miR-146b-5p is closely related to the proliferation and differentiation of chicken myogenic cells as a modulator of post-transcription....
Interestingly, miR-146b-5p (but not miR-146a-5p) was induced by IL-6-type cytokines (HIL-6 and OSM) in non-transformed liver-derived PH5CH8 and THLE2 cells and in Huh-7 hepatoma cells, but not in HepG2 or Hep3B hepatoma cells. We did not find evidence for a differential ...
目的:分离和鉴定甲状腺乳头状癌KTC-1细胞分泌的外泌体,并探讨外泌体携带miRNA146b-5p对KTC-1细胞体外迁移和侵袭的影响.方法:收集KTC-1细胞的外泌体,电转miRNA146b-5p和其抑制剂进入外泌体,并与KTC-1细胞共培养.检测KTC-1细胞的体外迁移和侵袭的能力.结果:成功分离和鉴定KTC-1细胞分泌的外泌体.外泌体miRNA...
Interestingly, miR‐146b‐5p (but not miR‐146a‐5p) was induced by IL‐6‐type cytokines (HIL‐6 and OSM) in non‐transformed liver‐derived PH5CH8 and THLE2 cells and in Huh‐7 hepatoma cells, but not in HepG2 or Hep3B hepatoma cells. We did not find evidence for a differential...
Though many miRNAs were investigated using various model mice,3 few studies have been reported on miRNA related to SS using IQI/Jic mice. In this study, we searched for new miRNAs related to SS in IQI/Jic mice using 3D-Gene method.
Plasma miRNA-146b-3p, -222-3p, -221-5p, -21a-3p Expression Levels and TSHR Methylation: Diagnostic Potential and Association with Clinical and Pathological Features in Papillary Thyroid CancerGENE expressionRECEIVER operating characteristic curves...
凋亡目的 探讨miRNA-146b-5p靶向调节线皮素-1(LAD-1)对非小细胞肺癌(NSCLC)增殖和凋亡的影响.方法 选取我院2018年3月至2021年1月接收的45例诊断为NSCLC并进行肿瘤根治术的患者,留存肿瘤组织及癌旁组织作为检测样本.采用RT-PCR检测样本中miRNA-146b-5p相对表达量.复苏NSCLC A549细胞,并建立稳定A549敲降miRNA-...