(3)除了这些特征明确的心脏特异性miRNA外,还出现了越来越多或有希望的候选miRNA,但大多数还需要进一步验证。 √2014年,Zhong等人发现,与对照组相比,AMI患者的循环miR-19a水平升高,表明其作为诊断AMI的血液生物标志物的潜在作用。此外,Mansouri等证实,AMI...
(mirnas)是一种在脊椎动物中内源性表达的单链短链rna,它们被认为是细胞蛋白表达的微调器,通过调控mrna翻译发挥作用,在癌症和非癌症细胞中,mirnas控制组织发育和分化、细胞生长和凋亡。 mirnas的异常调控参与了包括癌症在内的多种疾病的发病机制...
974 hsa-miR-5041,1224,06042,8689,302 hsa-miR-5052,1974,1908854,536 hsa-miR-5062,6671,3007,7943,038 hsa-miR-508332177393312 hsa-miR-5097581422196 hsa-miR-510635409398758 hsa-miR-512-3p28622856 hsa-miR-512-5p615415487829 hsa-miR-5132,5821,4871,1851,692 hsa-miR-5141108354,0901,477 hsa-miR-...
mature_mirnahsa-let-7ahsa-let-7bhsa-let-7chsa-let-7dhsa-let-7ehsa-let-7fhsa-let-7ghsa-miR-1hsa-miR-9hsa-miR-9*hsa-miR-10ahsa-miR-10bhsa-miR-15ahsa-miR-15bhsa-miR-16hsa-miR-17-3phsa-miR-17-5phsa-miR-18ahsa-miR-18bhsa-miR-19ahsa-miR-19bhsa-miR-20ahsa-miR-20bhsa-miR-...
Lopotová, T., Žáčková, M., Klamová, H., & Moravcová, J. (2011). MicroRNA-451 in chronic myeloid leukemia: MiR-451–BCR-ABL regulatory loop?Leukemia Research,35(7), 974–977. Lukiw, W. J. (2007). Micro-RNA speciation in fetal, adult and Alzheimer’s disease hippocampus...
疾病：NAFLD，CVD 表型：炎症 供体细胞：肝细胞 主变量：外泌体（miR-1） 交互变量：KLF4 效应变量：...
Nature, 2005, 435: 974～978. [ 4 ] Sonoki T, Iwanaga E, Mitsuya H, et al1 Insertion of m i2 croRNA - 125b - 1, a human homologue of lin - 4, into a rearranged immunoglobulin heavy chain gene locus in a pa2 tient with precursor B - cell acute lymphoblastic leukemia ...
(7044):974—978. 12.Karp X,Ambros V.Enhanced:encountering microRNAs in cell fate signaling[J].Science,2005,310(5752):1288—1289. 13.Chu CY。Rana TM.2007.Small RNAs:Regulators andguardiansofthe gun㈨e.Cell Physiology,213(2):412-419 14.Filipow iczW,Bhattaeharyya SN,Sonenberg N.2008.Mec...
miRNA的生物学特性和功能
974-983 CrossrefView in ScopusGoogle Scholar 25 R. Li, S. Luo, D. Zhang Circular RNA hsa_circ_0054537 sponges miR-130a-3p to promote the progression of renal cell carcinoma through regulating cMet pathway Gene (2020) 754:144811 Google Scholar 26 M. Wang, X. Wang, W. Liu MicroRNA-...