1HG的表达量明显降低(P<0.05).下调LncRNA MIR4435-1HG抑制AGS细胞增殖(P<0.05),阻碍其侵袭,迁移(P<0.05),诱导其凋亡(P<0.05).miR-150-5p是LncRNA MIR4435-1HG下游靶基因.结论 LncRNA MIR4435-1HG在多种胃癌细胞系中表达量上调;下调LncRNA MIR4435-1HG可能通过靶向miR-150-5p抑制AGS细胞增殖,侵袭,迁移...
订货号:0AC7457 品牌型号:Affymetrix 68427-01 货期:询货期 最小订货量:1套 +- Affymetrix 联系我们 400-920-3909 微信扫一扫,手机采购 商品介绍 规格参数 包装参数 Mir4435_1HG, HUMAN .440ml - ViewRNA TYPE 6,68427-01,Affymetrix 相关资料正在准备中......
Here, it was identified that lncRNA MIR4435‐2HG was highly expressed in lung cancer tissues, especially in nonsmall cell lung cancer (NSCLC). A consistent result was obtained in lung cancer cells. Functional experiments showed that knockdown of MIR4435‐2HG reduced the proliferation and ...
[目的]探讨长链非编码RNA MIR4435-2HG(LncRNA MIR4435-2HG)靶向上调转化生长因子-β1(TGF-β1)对非小细胞肺癌(NSCLC)细胞迁移,增殖的作用及其初步机制.[方法]检测NSCLC癌组织及其癌旁组织,NSCLC细胞株及正常人支气管上皮细胞(HBE)中MIR4435-2HG和TGF-β1表达.将pcDNA-MIR4435-2HG和pcDNA质粒转染至A549细胞...
TGF-beta 1The roles of long noncoding RNAs (lncRNAs) have been shown to play critical roles in tumor progression. Here, it was identified that lncRNA MIR4435-2HG was highly expressed in lung cancer tissues, especially in nonsmall cell lung cancer (NSCLC). A consistent result was obtained ...
Hepatic stellate cell‐released CXCL1 aggravates HCC malignant behaviors through the MIR4435‐2HG/miR‐506‐3p/TGFB1 axisdoi:10.1111/cas.15605Li, ShalingHu, XingwangYu, SongmanYi, PanpanChen, RuochanHuang, ZebingHuang, YanHuang, YunZhou, Rongrong...
Fig. 1 LncRNA-MIR4435-2HG is determined to be an oncogenic factor in FH-deficient RCC. A, B The bioinformation analysis showed upregulated lncRNAs in FH-deficient RCC tissues. C, D LncRNAs' expression determined both in fresh tumor samples and cell lines. E siRNA screeing was performed ...