miR-324-3p and SMAD4; enzyme-linked immunosorbent assay (ELISA) to determine the levels of serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST); and cell counting kit-8 (CCK-8) and flow cytometry to evaluate the effects of miR-324-3p on cell proliferation and cycle/...
We found that miR-324-5p had no effect on the mRNA level of Mtfr1 (Supplementary Figures 2A and B), whereas knockdown of endogenous miR-324-5p by antagomir induced an increase in Mtfr1 protein levels (Figure 3c), and enforced expression of miR-324-5p attenuated the increase of Mtfr1 p...
自前几天深受MOP上某位达人为一些反日发烧FQ医治感人事迹启发后(前段时间MOP上一群看到太阳就联想到日本的哥们,一发贴便就是不顶不是中国人之类的严重患者),发现我们现实中也有一些MIR3发烧友也或多或少患上有一些MIR3综合证,如:上街看到交警在查车便以为他们在堵门爆人,买衣服和鞋不看尺寸只看有没有强元素,...
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Here we report that NFAT4, miR-324-5p and mitochondrial fission regulator 1 (Mtfr1) function in one signaling axis that regulates mitochondrial morphology and cardiomyocyte cell death. Knocking down Mtfr1 suppresses mitochondrial fission, apoptosis and myocardial infarction. Mtfr1 is a direct target ...
Here we report that NFAT4, miR-324-5p and mitochondrial fission regulator 1 (Mtfr1) function in one signaling axis that regulates mitochondrial morphology and cardiomyocyte cell death. Knocking down Mtfr1 suppresses mitochondrial fission, apoptosis and myocardial infarction. Mtfr1 is a direct target ...