MIR-320E AND COLORECTAL CANCEREmbodiments provide methods and compositions related to determining treatments for colorectal cancer patients by detection and analysis of the expression level of miRNA such as miR-320e in the patients.AJAY GOELLUCIA PEREZ-CARBONELL...
PCR analysis, we found that cells cocultured with OPLL displayed increased miR-320e expression compared to controls (Fig.3E). Direct addition of OPLL cell-derived sEVs also significantly increased the cellular levels of miR-320e (Fig.3F). Overall, we confirmed miR-320e as an OPLL-sEV-specific...
110 MiR-320e Is a Prognostic and Predictive Biomarker in Colorectal Cancer - Gastroenterologydoi:10.1016/S0016-5085(14)60105-0Pérez-Carbonell, LucíaSinicrope, Frank A.Alberts, Steven R.Oberg, Ann L.Balaguer, FrancescCastells, AntoniBoland, C. Richard...
Embodiments provide methods and compositions related to determining treatments for colorectal cancer patients by detection and analysis of the expression level of miRNA such as miR-320e in the patients. Embodiments provide predictive, prognostic and/or diagnostics methods by identifying miRNAs that are ...
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MiR-320e inhibits proliferation in human umbilical vein endothelial cellsMicroRNAs(miRs)cardiovasculardiseasecoronaryarterydisease(CAD)Objective MicroR NAs(miRs)are a class of small non-coding RNAs,and have been shown to be critical regulators in pathology of cardiovascular disease,such as atherosclerosis...
Overall, exosomal miR-320e has the potential to be a novel biomarker for CSVD, but further research with a large sample size is necessary to assess its clinical utility.doi:10.2147/IJGM.S399338Ke-Jin GaoRui-Hua YinYuan WangZheng Wang
disease(CAD)Objective MicroR NAs(miRs)are a class of small non-coding RNAs,and have been shown to be critical regulators in pathology of cardiovascular disease,such as atherosclerosis,hypertension.We aimed to identify certain miR from differentially expressed miRs in coronary artery disease(CAD)...
MiR-320e is a novel prognostic biomarker in colorectal cancer. Br J Cancer 2015;113:83-90.Perez-Carbonell, L.,Sinicrope, F. A.,Alberts, S. R.,Oberg, A. L.,Balaguer, F.,Castells, A.,Boland, C. R.,Goel, A.. MiR-320e is a novel prognostic biomarker in colorectal cancer[J]....
72h时的DU145细胞活性,Cyclin D1,Bcl-2蛋白表达量(P<0.05),显著提高细胞凋亡率,P21,Bax蛋白水平(P<0.05).miR-320e靶向调控FHIT表达.抑制FHIT能逆转抑制miR-320e对细胞DU145增殖,Cyclin D1,Bcl-2蛋白表达的抑制作用,并逆转其对细胞凋亡,P21,Bax蛋白表达的促进作用.结论 miR-320e通过靶向调控FHIT影响前列腺癌...