生物信息学分析发现circ_0026134与miR-1270、miR-1270与GRB2存在潜在靶点,但circ_0026134、miR-1270和GRB2调控关系尚未有研究。本研究通过检测肝癌组织、细胞中circ_0026134、miR-1270、GRB2的表达情况,分析改变circ_0026134、miR-1270、G...
Research ArticleMiR-1270 Suppresses the Malignant Progression of BreastCancer via Targeting MMD2Shaojun Hu, 1 Yang Song, 2 Yu Zhou, 1 Yu Jiao, 1 and Song Wang3 , 41 Department of Oncological Surgery, First Af f i liated Hospital of Jiamusi University, Jiamusi, China2 Department of Pathology...
Meanwhile, miR-1270 inhibitor could invert the negative regulation effect of circ_0091579 silencing on YAP1 expression. Circ_0091579 promoted HCC progression by regulating the miR-1270/YAP1 axis, and our study might offer novel biomarkers and therapeutic targets for HCC. This is a preview of ...
Importantly, miR-330-5p/miR-1270-mediated repression of Pol I transcription exerted multiple tumor suppressive functions including reduced proliferation, cell cycle arrest, enhanced apoptosis, reduced migration, increased drug sensitivity, and reduced tumor burden in a mouse xenograft model. Mechanistically...
Janina VilsmaierJanina Vilsmaier,演员,参演电影《Bär ist los, Der》《爱上爱情》《Und keiner weint mir nach》《决战斯大林格勒》《拉玛·达玛》。 Alice FranzAlice Franz是一名演员,代表作品有《我的宝贝会乱说话》、《Vergeßt Mozart》等。
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